Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 1,190.00 | |
5 mg | In stock | $ 2,390.00 | |
10 mg | In stock | $ 3,220.00 | |
25 mg | In stock | $ 4,790.00 | |
50 mg | In stock | $ 6,460.00 | |
100 mg | In stock | $ 8,720.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 2,830.00 |
Description | 5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity. |
In vitro | 5-HT2 antagonist 1 displays dose-dependent inhibition of serotonin (erotonin)-induced contraction in guinea pig mesenteric artery, exhibiting 45%, 88%, and 93% inhibition at concentrations of 10 nM, 100 nM, and 1000 nM, respectively. Conversely, it demonstrates minimal inhibition of norepinephrine-induced contraction in guinea pig aorta, with 1% and 10% inhibition at 10 nM and 100 nM, respectively[1]. |
Molecular Weight | 400.49 |
Formula | C22H29FN4O2 |
CAS No. | 191592-09-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (112.36 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
5-HT2 antagonist 1 191592-09-3 GPCR/G Protein Neuroscience 5-HT Receptor 5HT2 antagonist 1 5 HT2 antagonist 1 5-HT-2 antagonist 1 inhibitor inhibit