7-FluorotryptaMine HCl

7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to study signalling pathways related to immunity and cancer.

Catalog No. T77673Cas No. 159730-09-3

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Purity:98.06%

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COA HPLC HNMR

7-FluorotryptaMine HCl

Catalog No. T77673Cas No. 159730-09-3

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

Pack Size	Price	Availability
1 mg	$31	In Stock
5 mg	$64	In Stock
10 mg	$105	In Stock
25 mg	$222	In Stock
50 mg	$333	In Stock
100 mg	$498	In Stock
500 mg	$1,130	In Stock

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Product Introduction

Bioactivity

Description	7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to study signalling pathways related to immunity and cancer.
In vitro	In the PRESTO-Tango assay, 7-FluorotryptaMine HCl (100 μM) hydrochloride induces GPRC5A recruitment of β-arrestin.[1] Co-treatment with 7-FluorotryptaMine HCl (50 μM, 8 h) and TNFα downregulates TNFα-induced genes (e.g., IL41A, CXCL10, CSF2) in WT and GPRC5A-KO cells [1]. 7-FluorotryptaMine HCl (0-100 μM, 16 h) is not toxic to mammalian cells (HTLA, HT-29 cells).[1]

Chemical Properties

Molecular Weight	214.67
Formula	C₁₀H₁₂ClFN₂
Cas No.	159730-09-3

Storage & Solubility Information

Storage

Shipping with blue ice.

Solubility Information

DMSO: 21.47 mg/mL (100 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.6583 mL	23.2916 mL	46.5831 mL	232.9156 mL
5 mM	0.9317 mL	4.6583 mL	9.3166 mL	46.5831 mL
10 mM	0.4658 mL	2.3292 mL	4.6583 mL	23.2916 mL
20 mM	0.2329 mL	1.1646 mL	2.3292 mL	11.6458 mL
50 mM	0.0932 mL	0.4658 mL	0.9317 mL	4.6583 mL
100 mM	0.0466 mL	0.2329 mL	0.4658 mL	2.3292 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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