Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 47.00 | |
10 mg | In stock | $ 83.00 | |
25 mg | In stock | $ 183.00 | |
50 mg | In stock | $ 328.00 | |
100 mg | In stock | $ 446.00 | |
200 mg | In stock | $ 580.00 | |
500 mg | In stock | $ 753.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 58.00 |
Description | AH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist. |
In vitro | AH7614 (0.063, 0.25, and 1μM) blocked linoleic acid and GSK137647A-induced intracellular calcium increase in U2OS osteosarcoma cells expressing the FFA4 receptor. In addition, the increase of glucose-stimulated insulin secretion by GSK137647A (50 μM) was abolished in the presence of the selective FFA4 antagonist AH7614 (100 μM) in the MIN6 mouse insulinoma cell line. Moreover, AH7614 (100 μM) blocked GSK137647A (100μM)-mediated a modest increase of GLP-1 secretion in the NCIH716 cells. |
Synonyms | AH 7614 |
Molecular Weight | 351.42 |
Formula | C20H17NO3S |
CAS No. | 6326-06-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 35.1 mg/mL(100 mM)
Ethanol: Insoluble
H2O: Insoluble
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AH-7614 6326-06-3 Endocrinology/Hormones GPCR/G Protein GPR allosteric linoleic negative FFAR GPR120 FFA4 inhibit AH7614 NAM Inhibitor Free Fatty Acid Receptor AH 7614 acid inhibitor