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CAY10471 Racemate

Catalog No. T7359 CAS 844639-57-2

Synonyms: 3-[[(4-氟苯基)磺酰基]甲基氨基]-1,2,3,4-四氢-9H-咔唑-9-乙酸, TM30089 Racemate

CAY 10471 is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2, DP1, and TP receptors( Ki values of 0.6, 1200, and >10,000 nM,respectively)

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CAY10471 Racemate, CAS 844639-57-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	CAY 10471 is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2, DP1, and TP receptors( Ki values of 0.6, 1200, and >10,000 nM,respectively)
Targets&IC50	CRTH2:0.6 nM(ki) , DP:1200 nM(ki)

Synonyms	3-[[(4-氟苯基)磺酰基]甲基氨基]-1,2,3,4-四氢-9H-咔唑-9-乙酸, TM30089 Racemate
Molecular Weight	416.47
Formula	C21H21FN2O4S
CAS No.	844639-57-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 150 mg/mL (360.17 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Ulven T , Kostenis E . Minor Structural Modifications Convert the Dual TP/CRTH2 Antagonist Ramatroban into a Highly Selective and Potent CRTH2 Antagonist[J]. Journal of Medicinal Chemistry, 2005, 48(4):897-900.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Endocrinology-Hormone Compound Library Inhibitor Library Bioactive Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CAY10471 Racemate 844639-57-2 G蛋白偶联受体免疫与炎症内分泌与激素 GPR Prostaglandin Receptor CAY 10471 CAY10471 TM30089 Inhibitor CAY-10471 TM 30089 TM-30089 inhibit CAY-10471 Racemate TM30089 Racemate inhibitor

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