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Chromocarb

Catalog No. T0259 CAS 4940-39-0

Synonyms: Chromone-2-carboxylic acid, Chromocarbe

Chromocarb (Chromone-2-carboxylic acid) is a vascular protective agent used to treat venous disorders and microvascular affections.

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Chromocarb, CAS 4940-39-0

Pack Size	Availability	Price/USD	Quantity
500 mg	In stock	$ 42.00
1 mL * 10 mM (in DMSO)	In stock	$ 46.00

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Purity: 99.88%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Chromocarb (Chromone-2-carboxylic acid) is a vascular protective agent used to treat venous disorders and microvascular affections.

In vitro

Rats treated orally with Chromocarb exhibited a significant reduction in vascular wall degradation induced by intravenous collagenase. Chromocarb treatment led to a decreased increase in BBB (blood-brain barrier) permeability, accelerated recovery, lower hydroxyproline levels in cerebrospinal fluid, and a lesser decline in collagen content within the cerebral capillary basement membranes. Furthermore, at a dose of 50 mg/kg, Chromocarb was more effective than vitamin C at preventing the oxidation of reduced glutathione in the blood.

Synonyms	Chromone-2-carboxylic acid, Chromocarbe
Molecular Weight	190.15
Formula	C10H6O4
CAS No.	4940-39-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 36 mg/mL (189.3 mM)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

References and Literature

1. Godeau G, et al. Clin Physiol Biochem, 1987, 5(1), 15-26. 2. Márquez R, et al. Pharmacol Toxicol, 2001, 89(5), 255-258

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Drug-Fragment Library Approved Drug Library Carboxylic Acid Fragment Library With Solubility Human Metabolite Library Anti-Cardiovascular Disease Compound Library Bioactive Compounds Library Max NO PAINS Compound Library Bioactive Compound Library Immunology/Inflammation Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Chromocarb 4940-39-0 Others Chromone-2-carboxylic acid Chromocarbe inhibit Inhibitor inhibitor

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