Shopping Cart
- Remove All
- Your shopping cart is currently empty
Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $157 | In Stock | |
5 mg | $388 | In Stock | |
10 mg | $553 | In Stock | |
25 mg | $828 | In Stock | |
50 mg | $1,110 | In Stock | |
100 mg | $1,490 | In Stock | |
500 mg | $2,950 | In Stock | |
1 mL x 10 mM (in DMSO) | $426 | In Stock |
Description | Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM). |
Targets&IC50 | Chymase:29 nM |
In vitro | Chymase-IN-1 (compound 5f) exhibits a chymase Ki value of 36 nM and a Cat G Ki value of 9500 nM[1]. |
In vivo | Chymase-IN-1 shows low oral bioavailability in rats (F=3%; oral t1/2=1.8 h)[1]. |
Molecular Weight | 431.83 |
Formula | C20H15ClNO4PS |
Cas No. | 862090-74-2 |
Smiles | C(C(NC1=CC2=C(C=C1)C=CC=C2)=O)(P(=O)(O)O)C=3C=4C(SC3)=CC=C(Cl)C4 |
Relative Density. | 1.583 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (115.79 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.