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DS08210767

Catalog No. T11101Cas No. 2376334-75-5

DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with an IC50 of 90 nM.

DS08210767

DS08210767

Purity: 98.33%
Catalog No. T11101Cas No. 2376334-75-5
DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with an IC50 of 90 nM.
Pack SizePriceAvailabilityQuantity
1 mg$129In Stock
5 mg$322In Stock
10 mg$466In Stock
25 mg$693In Stock
50 mg$954In Stock
100 mg$1,300In Stock
500 mg$2,610In Stock
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Purity:98.33%
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Product Introduction

Bioactivity
Description
DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with an IC50 of 90 nM.
Targets&IC50
PTHR1:90 nM
Chemical Properties
Molecular Weight513.67
FormulaC31H39N5O2
Cas No.2376334-75-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.5 mg/mL (8.8 mM), Sonication and heating to 80℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9468 mL9.7339 mL19.4678 mL97.3388 mL
5 mM0.3894 mL1.9468 mL3.8936 mL19.4678 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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