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Eberconazole Nitrate

Catalog No. T7824Cas No. 130104-32-4
Alias Ebernet

Eberconazole Nitrate (Ebernet) is an azole antifungal agent and broad-spectrum imidazole derivative.

Eberconazole Nitrate

Eberconazole Nitrate

Purity: 99.53%
Catalog No. T7824Alias EbernetCas No. 130104-32-4
Eberconazole Nitrate (Ebernet) is an azole antifungal agent and broad-spectrum imidazole derivative.
Pack SizePriceAvailabilityQuantity
2 mg$40In Stock
5 mg$64In Stock
10 mg$97In Stock
25 mg$213In Stock
50 mg$322In Stock
100 mg$488In Stock
1 mL x 10 mM (in DMSO)$76In Stock
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Purity:99.53%
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Product Introduction

Bioactivity
Description
Eberconazole Nitrate (Ebernet) is an azole antifungal agent and broad-spectrum imidazole derivative.
In vivo
Spherical and porous Eberconazole Nitrate(EB) microsponge particles were obtained.?The optimized microsponges possessed particle size, drug content and entrapment efficiency of 24.5 μm, 43.31% and 91.44%, respectively.?Microsponge-loaded gels demonstrated controlled release, nonirritancy to rat skin and antifungal activity.?An in vivo skin deposition study demonstrated fourfold higher retention in the stratum corneum layer as compared with commercial cream[1].
Animal Research
Eberconazole Nitrate(EB) microsponges were prepared using the quasiemulsion solvent diffusion method.?The effect of formulation variables (drug:polymer ratio, internal phase volume and amount of emulsifier) and process variables (stirring time and stirring speed) on the physical characteristics of microsponges were investigated.?The optimized microsponges were dispersed into a hydrogel and evaluated[1].
AliasEbernet
Chemical Properties
Molecular Weight392.23
FormulaC18H15Cl2N3O3
Cas No.130104-32-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (63.74 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5495 mL12.7476 mL25.4952 mL127.4762 mL
5 mM0.5099 mL2.5495 mL5.0990 mL25.4952 mL
10 mM0.2550 mL1.2748 mL2.5495 mL12.7476 mL
20 mM0.1275 mL0.6374 mL1.2748 mL6.3738 mL
50 mM0.0510 mL0.2550 mL0.5099 mL2.5495 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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