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HS 014 acetate(207678-81-7 free base)

Catalog No. TP2015L CAS TP2015L

HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central administration in vivo. Also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus.

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HS 014 acetate(207678-81-7 free base) Chemical Structure

HS 014 acetate(207678-81-7 free base), CAS TP2015L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 308.00
5 mg	In stock	$ 695.00
10 mg	In stock	$ 929.00
25 mg	In stock	$ 1,390.00
50 mg	In stock	$ 1,880.00
100 mg	In stock	$ 2,530.00

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Purity: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	1623.83
Formula	C73H98N20O19S2
CAS No.	TP2015L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

References and Literature

1. Bellasio et al (2003) Melanocortin receptor agonists and antagonists modulate nociceptive sensitivity in the mouse formalin test. Eur.J.Pharmacol. 482 127 PMID: 2. Schioth et al (1998) Discovery of novel melanocortin4 receptor selective MSH analogues. Br.J.Pharmacol. 124 75 PMID: 3. Whitaker and Reye (2008) Central blockade of melanocortin receptors attenuates the metabolic and locomotor responses to peripheral interleukin-1β administration. Neuropharmacology 54 509 PMID:

Related compound libraries

This product is contained In the following compound libraries：

Neuronal Signaling Compound Library GPCR Compound Library NO PAINS Compound Library Bioactive Compounds Library Max Inhibitor Library Peptide Compound Library Bioactive Compound Library Anti-Obesity Compound Library

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Related compounds with same targets

TCMCB07 TFA PG 106 acetate Melanotan (MT)-II IIIM-8 JNJ-10229570 PF-07258669 Dersimelagon Undecylenoyl phenylalanine

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Keywords

HS 014 acetate(207678-81-7 free base) TP2015L GPCR/G Protein Neuroscience Melanocortin Receptor HS 014 acetate(207678 81 7 free base) HS 014 acetate(207678817 free base) inhibitor inhibit

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