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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $33 | In Stock | |
25 mg | $65 | In Stock | |
50 mg | $118 | In Stock | |
100 mg | $221 | In Stock | |
200 mg | $329 | In Stock | |
1 mL x 10 mM (in DMSO) | $34 | In Stock |
Description | JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively). |
Targets&IC50 | MAGL (rat):14 nM, MAGL (human):3.7 nM, MAGL:7.6 nM(mouse) |
In vitro | MAGL inhibitor JW 642 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s: 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively). |
Molecular Weight | 462.39 |
Formula | C21H20F6N2O3 |
Cas No. | 1416133-89-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90 mg/mL (194.64 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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