Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 34.00 | |
10 mg | In stock | $ 55.00 | |
25 mg | In stock | $ 109.00 | |
50 mg | In stock | $ 197.00 | |
100 mg | In stock | $ 369.00 | |
200 mg | In stock | $ 549.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 57.00 |
Description | JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively). |
Targets&IC50 | MAGL (human):3.7 nM, MAGL (rat):14 nM, MAGL:7.6 nM(mouse) |
In vitro | MAGL inhibitor JW 642 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s: 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively). |
Molecular Weight | 462.39 |
Formula | C21H20F6N2O3 |
CAS No. | 1416133-89-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (194.64mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JW 642 1416133-89-5 Metabolism Lipase MAGL inhibit Inhibitor JW642 JW-642 Monoacylglycerol lipase inhibitor