Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16 μM for KDM2A.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 2,120.00 | |
50 mg | In stock | $ 2,780.00 | |
100 mg | In stock | $ 3,700.00 |
Description | KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16 μM for KDM2A. |
Targets&IC50 | KDM2A:0.16 μM |
In vitro | KDM2A/7A-IN-1 (0.4, 3.1, 6.2 μM) augments cellular H3K36me2 levels in HeLa cells ectopically expressing catalytically active KDM2A.KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16?μM for KDM2A, exhibits 75 fold selevtivity over other JmjC lysine demethylases, and is inactive to methyl transferases, and histone acetyl transferases. |
Molecular Weight | 506.68 |
Formula | C33H38N4O |
CAS No. | 2169272-46-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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KDM2A/7A-IN-1 2169272-46-0 Others KDM2A/7AIN1 KDM2A/7A IN 1 KDM-2A/7A-IN-1 inhibitor inhibit