Powder: -20°C for 3 years
In solvent: -80°C for 2 years
LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.
Description | LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a. |
Targets&IC50 | hGlyT1:15.8 nM nM |
In vivo | LY2365109 hydrochloride increases seizure thresholds in mice[2].LY2365109 hydrochloride (0.3-30 mg/kg; p.o.) produces dose-dependent elevations in CSF levels of glycine[1].? |
Synonyms | LY2365109盐酸盐 |
Molecular Weight | 421.91 |
Formula | C22H28ClNO5 |
CAS No. | 1779796-27-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 30 mg/mL (71.11 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LY2365109 hydrochloride 1779796-27-8 神经科学 GlyT neuroblastoma Glycine transporters LY2365109 Human LY-2365109 hydrochloride LY 2365109 glycine seizure LY-2365109 uptake Inhibitor inhibit inhibitor