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MALTOTETRAOSE

Catalog No. T5785   CAS 34612-38-9
Synonyms: Fujioligo 450, Amylotetraose, α-1,4-Tetraglucose

Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development.

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MALTOTETRAOSE Chemical Structure
MALTOTETRAOSE, CAS 34612-38-9
Pack Size Availability Price/USD Quantity
5 mg In stock $ 42.00
10 mg In stock $ 66.00
25 mg In stock $ 97.00
50 mg In stock $ 158.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development.
In vivo Maltotetraose reduced PDGF-induced sprout formation by mouse aorta explants and inhibited TNF-α-induced NF-κB activation and ICAM-1 expression in MOVAS-1 cells[1].
Animal Research Ex vivo migration of VSMCs was measured by aortic . Mouse thoracic aortas were excised from 8-week-old male Balb/c mice and adipose tissue was removed. The aortas were sectioned into 1-mm–long cross-sections, rinsed with serum-free DMEM, treated with 1 mg/mL collagenenase type II, placed in matrigel-coated wells, covered with 50 uL matrigel, and allowed to gel for more than 30 min at 37℃ in a 5% CO2 atmosphere. The aortic rings were treated with 20 ug/mL MALTOTETRAOSE for 30 min, followed by stimulation with 20 ng/mL PDGF-BB. Aortic ring sprouts were photographed on day 7[1].
Synonyms Fujioligo 450, Amylotetraose, α-1,4-Tetraglucose
Molecular Weight 666.58
Formula C24H42O21
CAS No. 34612-38-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (82.51 mM)

TargetMolReferences and Literature

1. Shin S Y , Jung J Y , Yong Y , et al. Inhibition of PDGF-induced migration and TNFα-induced ICAM-1 expression by maltotetraose from bamboo stem extract (BSE) in mouse vascular smooth muscle cells[J]. Molecular Nutrition & Food Research, 2016, 60(9):2086-2097. 2. Arfelli G , Sartini E . Characterisation of brewpub beer carbohydrates using high performance anion exchange chromatography coupled with pulsed amperometric detection[J]. Food Chemistry, 2014, 142:152-158.

Related compound libraries

This product is contained In the following compound libraries:
Inhibitor Library Human Endogenous Metabolite Library Traditional Chinese Medicine Monomer Library Food as Medicine Compound Library Bioactive Compounds Library Max Anti-Aging Compound Library Bioactive Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library HIF-1 Signaling Pathway Compound Library Pyroptosis Compound Library

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Keywords

MALTOTETRAOSE 34612-38-9 Apoptosis Metabolism TNF Endogenous Metabolite Fujioligo-450 Inhibitor Fujioligo 450 inhibit Amylotetraose a-1,4-Tetraglucose α-1,4-Tetraglucose Fujioligo450 alpha-1,4-Tetraglucose inhibitor

 

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