Shopping Cart
- Remove All
Your shopping cart is currently empty
MK 1903
MK 1903 is a potent and selective complete agonist for the hydroxy-carboxylic acid receptor 2 (HCA2). HCA2 is also known as G protein-coupled receptor 109A(GPR109A). MK 1903 reduced Foschlin-induced cAMP production in uniform time-resolved fluorescence (htf) measurements using CHO cells expressing the human receptor (ECso-12.9 nM).
Catalog No. T22986Cas No. 1268882-43-4
Select Batch
Purity:98%
Contact us for more batch information
Resource Download
MK 1903
Catalog No. T22986Cas No. 1268882-43-4
MK 1903 is a potent and selective complete agonist for the hydroxy-carboxylic acid receptor 2 (HCA2). HCA2 is also known as G protein-coupled receptor 109A(GPR109A). MK 1903 reduced Foschlin-induced cAMP production in uniform time-resolved fluorescence (htf) measurements using CHO cells expressing the human receptor (ECso-12.9 nM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $42 | In Stock | |
| 5 mg | $98 | In Stock | |
| 10 mg | $147 | In Stock | |
| 25 mg | $263 | In Stock | |
| 50 mg | $368 | In Stock | |
| 100 mg | $518 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "MK 1903"
Benzyl nicotinate
Rubriment, Pycaril
T771394-44-0
Benzyl nicotinate (Pycaril) is a agonist of GPR109A receptor and GPR109B receptor
- $29
Size
QTY
Monomethyl fumarate
T120952756-87-8
Monomethyl fumarate is a potent agonist of GPR109A .
- $42
Size
QTY
Vincamine
Perval, Oxybral, Novicet, Equipur, Devincan, Angiopac
T12861617-90-9
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.
- $40
Size
QTY
TUG-1375
Cited
T77962247372-59-2
TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2
- $81
Size
QTY
CitedQuestiomycin A
T368181916-59-2
Questiomycin A is an antibiotic produced in crème fraiche with antibacterial and anticancer activities. Questiomycin A suppresses expression of GRP78, a cell-protective ER chaperone protein.
- $29
Size
QTY
CRTh2 antagonist 2
T10889780763-95-3In house
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
- $109
Size
QTY
1-methoxycyclopropanecarboxylic acid
T9437100683-08-7
1-methoxycyclopropanecarboxylic acid is an agonist of free fatty acid receptor 3 (FFAR3, human).
- $30
Size
QTY
Fezagepras sodium
Setogepram sodium salt, PBI-4050 sodium salt
T123751254472-97-3In house
Fezagepras sodium (Setogepram sodium salt) is an orally active GPR40 agonist and is an antagonist or inverse agonist for GPR84, with anti-fibrotic, anti-inflammatory and anti-proliferative actions.
- $36
Size
QTY
CAY10595
T10691916047-16-0In house
CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.
- $46
Size
QTY
Timapiprant
OC000459
T2664851723-84-7
Timapiprant (OC000459) is a potent and selective D prostanoid receptor 2 (DP2) antagonist (IC50: 13 nM).
- $29
Size
QTY
NF-56-EJ40
T122162380230-73-7
NF-56-EJ40 is an effective and highly selective antagonist of human SUCNR1 with an IC50 of 25 nM and a Ki of 33 nM.
- $83
Size
QTY
3-Hydroxyoctanoic Acid
T971914292-27-4
3-Hydroxyoctanoic Acid is one of the hydroxy-carboxylic acids (HCAs) that serve as intermediates of energy metabolism. It is an agonist of the orphan receptor GPR109B.
- $31
Size
QTY
Product Introduction
Bioactivity
Chemical Properties
| Description | MK 1903 is a potent and selective complete agonist for the hydroxy-carboxylic acid receptor 2 (HCA2). HCA2 is also known as G protein-coupled receptor 109A(GPR109A). MK 1903 reduced Foschlin-induced cAMP production in uniform time-resolved fluorescence (htf) measurements using CHO cells expressing the human receptor (ECso-12.9 nM). |
| In vivo | MK-1903 (Compound R, R-19a ) was well tolerated and produced a robust decrease in plasma-free fatty acids.[1] |
| Molecular Weight | 164.16 |
| Formula | C8H8N2O2 |
| Cas No. | 1268882-43-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: < 8.21 mg/mL DMSO: 112.5 mg/mL (685.3 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy MK 1903 | purchase MK 1903 | MK 1903 cost | order MK 1903 | MK 1903 chemical structure | MK 1903 in vivo | MK 1903 formula | MK 1903 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.