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Maxacalcitol

Catalog No. T16015Cas No. 103909-75-7
Alias 22-Oxacalcitriol

Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue. Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo.

Maxacalcitol

Maxacalcitol

Catalog No. T16015Alias 22-OxacalcitriolCas No. 103909-75-7
Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue. Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo.
Pack SizePriceAvailabilityQuantity
1 mg$97In Stock
5 mg$363In Stock
10 mg$563In Stock
25 mg$1,120In Stock
50 mg$1,790In Stock
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Purity:≥98%
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Product Introduction

Bioactivity
Description
Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue. Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo.
In vitro
Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Maxacalcitol inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid. Maxacalcitol shows similar effects to calcitriol in osteoblast-like cells.
Alias22-Oxacalcitriol
Chemical Properties
Molecular Weight418.61
FormulaC26H42O4
Cas No.103909-75-7
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (238.89 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3889 mL11.9443 mL23.8886 mL119.4429 mL
5 mM0.4778 mL2.3889 mL4.7777 mL23.8886 mL
10 mM0.2389 mL1.1944 mL2.3889 mL11.9443 mL
20 mM0.1194 mL0.5972 mL1.1944 mL5.9721 mL
50 mM0.0478 mL0.2389 mL0.4778 mL2.3889 mL
100 mM0.0239 mL0.1194 mL0.2389 mL1.1944 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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