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Nanterinone (UK 61260), an orally available partial phosphodiesterase inhibitor, is a novel positive inotropic and balanced vasodilator compound.Nanterinone, when administered orally, results in significant improvements in acute haemodynamics, which may depend on pre-existing left ventricular filling pressures.Nanterinone is a novel positive inotropic and balanced vasodilator that has demonstrated acute hemodynamic effects in patients with mild to moderate heart failure.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $143 | In Stock | |
5 mg | $360 | In Stock | |
10 mg | $530 | In Stock | |
25 mg | $859 | In Stock | |
50 mg | $1,180 | In Stock | |
100 mg | $1,590 | In Stock | |
500 mg | $3,190 | In Stock |
Description | Nanterinone (UK 61260), an orally available partial phosphodiesterase inhibitor, is a novel positive inotropic and balanced vasodilator compound.Nanterinone, when administered orally, results in significant improvements in acute haemodynamics, which may depend on pre-existing left ventricular filling pressures.Nanterinone is a novel positive inotropic and balanced vasodilator that has demonstrated acute hemodynamic effects in patients with mild to moderate heart failure. |
In vivo | Nanterinone (2 mg ; oral ; patients NYHA class II-III ; ACE) has a significant acute hemodynamic improvement and is well tolerated. Although changes in left ventricular filling pressure are more pronounced in patients with elevated pre-existing PCWP, cardiac pump function improves equally in patients with normal or low left ventricular filling pressure at baseline.[1] |
Alias | UK-61260, UK61260, UK 61260 |
Molecular Weight | 253.3 |
Formula | C15H15N3O |
Cas No. | 102791-47-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: Slightly soluble |
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