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Nanterinone

Nanterinone
Nanterinone (UK 61260), an orally available partial phosphodiesterase inhibitor, is a novel positive inotropic and balanced vasodilator compound.Nanterinone, when administered orally, results in significant improvements in acute haemodynamics, which may depend on pre-existing left ventricular filling pressures.Nanterinone is a novel positive inotropic and balanced vasodilator that has demonstrated acute hemodynamic effects in patients with mild to moderate heart failure.
Catalog No. T33589Cas No. 102791-47-9
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Purity:99.11%
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Nanterinone

Purity: 99.11%
Catalog No. T33589Alias UK-61260, UK61260, UK 61260Cas No. 102791-47-9

Nanterinone (UK 61260), an orally available partial phosphodiesterase inhibitor, is a novel positive inotropic and balanced vasodilator compound.Nanterinone, when administered orally, results in significant improvements in acute haemodynamics, which may depend on pre-existing left ventricular filling pressures.Nanterinone is a novel positive inotropic and balanced vasodilator that has demonstrated acute hemodynamic effects in patients with mild to moderate heart failure.
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Pack SizePriceAvailabilityQuantity
1 mg$143In Stock
5 mg$360In Stock
10 mg$530In Stock
25 mg$859In Stock
50 mg$1,180In Stock
100 mg$1,590In Stock
500 mg$3,190In Stock
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Product Introduction

Bioactivity
Description
Nanterinone (UK 61260), an orally available partial phosphodiesterase inhibitor, is a novel positive inotropic and balanced vasodilator compound.Nanterinone, when administered orally, results in significant improvements in acute haemodynamics, which may depend on pre-existing left ventricular filling pressures.Nanterinone is a novel positive inotropic and balanced vasodilator that has demonstrated acute hemodynamic effects in patients with mild to moderate heart failure.
In vivo
Nanterinone (2 mg ; oral ; patients NYHA class II-III ; ACE) has a significant acute hemodynamic improvement and is well tolerated. Although changes in left ventricular filling pressure are more pronounced in patients with elevated pre-existing PCWP, cardiac pump function improves equally in patients with normal or low left ventricular filling pressure at baseline.[1]
AliasUK-61260, UK61260, UK 61260
Chemical Properties
Molecular Weight253.3
FormulaC15H15N3O
Cas No.102791-47-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: Slightly soluble

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