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Naringenin
Catalog No. T2838Cas No. 480-41-1
Alias S-Dihydrogenistein, Salipurol, Pelargidanon, NSC 34875, NSC 11855, Naringetol
Naringenin (NSC-11855) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. This substance has also been shown to repair DNA.
Naringenin
Catalog No. T2838Alias S-Dihydrogenistein, Salipurol, Pelargidanon, NSC 34875, NSC 11855, NaringetolCas No. 480-41-1
Naringenin (NSC-11855) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. This substance has also been shown to repair DNA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $50 | In Stock | |
| 100 mg | $53 | In Stock | |
| 500 mg | $81 | In Stock | |
| 1 g | $120 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $57 | In Stock |
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Purity:99.55%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Naringenin (NSC-11855) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. This substance has also been shown to repair DNA. |
| In vitro | In both normoglycemic and non-insulin-dependent diabetes mellitus rat models, oral administration of 50 mg/kg Naringenin resulted in a significant decrease in plasma glucose levels. |
| In vivo | Naringenin, found in grapefruit juice, has been demonstrated to inhibit the human cytochrome P450 isoform CYP1A2. This can adversely alter the pharmacokinetics of several common agents in human (or directly homologous) hosts, potentially rendering otherwise harmless substances carcinogenic. |
| Cell Research | Naringenin is dissolved in DMSO and diluted in cell culture medium. The cells are rinsed with PBS and grown in a medium containing various concentrations of naringenin (50, 100, 150, 200, 250, 300 μM). The solvent DMSO treated cells are served as control. After 24 hrs of treatment, the medium is removed and replaced by another medium containing MTT. Cell viability is measured using the MTT assay[1]. |
| Alias | S-Dihydrogenistein, Salipurol, Pelargidanon, NSC 34875, NSC 11855, Naringetol |
| Molecular Weight | 272.25 |
| Formula | C15H12O5 |
| Cas No. | 480-41-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 18.33 mg/mL (67.34 mM)  Ethanol: 5 mg/mL (18.36 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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