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Neohesperidin
Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.
Catalog No. T2737Cas No. 13241-33-3
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Purity:98.34%
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Neohesperidin
Catalog No. T2737Alias NSC 31048, Hesperetin 7-O-neohesperidosideCas No. 13241-33-3
Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $39 | In Stock | |
| 100 mg | $51 | In Stock | |
| 500 mg | $189 | In Stock | |
| 1 g | $312 | In Stock | |
| 5 g | $713 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $43 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model. |
| In vivo | Neohesperidin, administered at a dose of 50 mg/kg, significantly reduces the occurrence of HCl/ethanol-induced gastric lesions by 55.0%. In studies involving pylorus-ligated rats, this compound notably decreases both the volume of gastric secretion and gastric acid output, while simultaneously increasing gastric pH[1]. Additionally, neohesperidin treatment markedly improves glucose metabolism and insulin sensitivity in diabetic mice, evidenced by substantial reductions in fasting glucose, serum glucose, glycosylated serum protein (GSP), serum triglycerides, total cholesterol, and leptin levels, alongside a decrease in the liver index. It also enhances oral glucose tolerance and reduces insulin resistance in these mice[3]. |
| Alias | NSC 31048, Hesperetin 7-O-neohesperidoside |
| Molecular Weight | 610.56 |
| Formula | C28H34O15 |
| Cas No. | 13241-33-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (81.89 mM)  H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: < 1 mg/mL (insoluble or slightly soluble) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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