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Norethynodrel

Catalog No. T0171 CAS 68-23-5

Synonyms: Lynestrol

Norethynodrel (Lynestrol) is a synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combination with MESTRANOL.

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Norethynodrel, CAS 68-23-5

Pack Size	Availability	Price/USD	Quantity
1 mg	4-5 weeks	$ 296.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Kinase Assay

Assay of glutamate released: Hippocampal slices (400 μM) are prepared from the guinea pig brain using standard techniques. A slice is fixed on a pair of silver wire electrodes (10 Hz, 5 V, 0.1 ms in duration) at 1-minutes intervals for 10 minutes and submerged in 1 mL standard artificial cerebrospinal fluid (ACSF) (in mM: 125 mM NaCl, 5 mM KCl, 1.24 mM KH2PO4, 1.3 mM MgSO4, 2 mM CaCl2, 26 mM NaHCO3, and 10 mM glucose) oxygenated with 95% O2 and 5% CO2 at 36 °C in the presence and absence of tetrodotoxin (TTX) (0.5 μM). In a different set of experiments, electrical stimulation is applied to slices treated with Nefiracetam (1 μM) in the presence and absence of α-bungarotoxin (50 nM) or mecamylamine (3 μM). A 100 μL aliquot of the medium filtered with millipore filters (0.45 μM) is injected onto the cation-exchanger column of the autoanalyser to separate amino acids and the amount of glutamate released is calculated using known amino acid standard concentrations.

Synonyms	Lynestrol
Molecular Weight	298.42
Formula	C20H26O2
CAS No.	68-23-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 8.95 mg/L

References and Literature

1. Edgren RA. Steroids. 1994 Jan;59(1):58-9.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Norethynodrel 68-23-5 Endocrinology/Hormones Estrogen/progestogen Receptor NSC 15432 SC-4642 progestagen Lynestrol NSC-15432 inhibit SC4642 Enidrel Endogenous Metabolite Inhibitor inhibition of ovulation NSC15432 SC 4642 inhibitor

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