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Oxaloacetic acid

Catalog No. T4862   CAS 328-42-7

Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) is formed by the oxidation of L-malate, catalyzed by malate dehydrogenase, and reacts with Acetyl-CoA to form citrate, catalyzed by citrate synthase.(wikipedia) A class of ketodicarboxylic acids derived from oxalic acid. Oxaloacetic acid is an intermediate in the citric acid cycle and is converted to aspartic acidD by a transamination reaction.

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Oxaloacetic acid Chemical Structure
Oxaloacetic acid, CAS 328-42-7
Pack Size Availability Price/USD Quantity
500 mg In stock $ 42.00
1 mL * 10 mM (in DMSO) In stock $ 30.00
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Purity: 99.25%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) is formed by the oxidation of L-malate, catalyzed by malate dehydrogenase, and reacts with Acetyl-CoA to form citrate, catalyzed by citrate synthase.(wikipedia) A class of ketodicarboxylic acids derived from oxalic acid. Oxaloacetic acid is an intermediate in the citric acid cycle and is converted to aspartic acidD by a transamination reaction.
Molecular Weight 132.07
Formula C4H4O5
CAS No. 328-42-7

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 196.9 mM

TargetMolReferences and Literature

1. Sweatman B C , Farrant R D , Holmes E , et al. 600 MHz 1H-NMR spectroscopy of human cerebrospinal fluid: effects of sample manipulation and assignment of resonances.[J]. Journal of Pharmaceutical & Biomedical Analysis, 1993, 11(8):651-64. 2. Efimov A S , Gulyĭ MF, Shcherbak A V , et al. [Levels of Krebs cycle metabolites in the blood and urine of patients with diabetes mellitus][J]. Problemy Endokrinologii, 1983, 29(2):10. 4. Zupke C , Sinskey A J , Stephanopoulos G . Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas.[J]. Appl Microbiol Biotechnol, 1995, 44(1-2):27-36. 5. Dworzak E , Grunicke H , Berger H , et al. [Pyruvate dehydrogenase deficiency in a child with persistent lactic acidosis][J]. J Clin Chem Clin Biochem, 1985, 23(6):323-329.

Related compound libraries

This product is contained In the following compound libraries:
Human Endogenous Metabolite Library Tobacco Monomer Library Drug Repurposing Compound Library NO PAINS Compound Library Human Metabolite Library Bioactive Compounds Library Max Natural Product Library for HTS Bioactive Compound Library RO5 Drug-like Natural Product Library Natural Product Library

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Keywords

Oxaloacetic acid 328-42-7 Metabolism Endogenous Metabolite Inhibitor inhibit 2-Oxosuccinic acid metabolic,TCA cycle inhibitor

 

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