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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $38 | In Stock | |
10 mg | $52 | In Stock | |
25 mg | $82 | In Stock | |
50 mg | $138 | In Stock | |
100 mg | $198 | In Stock | |
200 mg | $297 | In Stock | |
500 mg | $512 | In Stock | |
1 mL x 10 mM (in H2O) | $42 | In Stock |
Description | Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones. |
In vitro | In ovariectomized rats, Pamidronate significantly enhanced bone density and trabecular weight. Additionally, in rats treated with Growth Hormone (GH), Pamidronate reduced the levels of IGF-I. |
In vivo | In human osteoblast-like cells, Pamidronate (1 μM) enhances the level of OPG mRNA and protein secretion in a dose-dependent manner. Additionally, in mouse osteoclast-like cells (IC50=0.58 μM), Pamidronate inhibits the resorption of calcium phosphate films. |
Alias | CGP 23339A, CGP 23339AE, Pamidronate disodium salt |
Molecular Weight | 279.03 |
Formula | C3H9NNa2O7P2 |
Cas No. | 57248-88-1 |
Storage | |||||||||||||||||||||
Solubility Information | DMSO: Insoluble H2O: 10 mM | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
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