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Pinobanksin 3-acetate

Catalog No. TN2967 CAS 52117-69-8

Synonyms: 3-O-Acetylpinobanksin

Pinobanksin 3-acetate (3-O-Acetylpinobanksin), a flavonoid derivative, is a strong antioxidant found in sunflowers and honey that inhibits LDL peroxidation.

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Pinobanksin 3-acetate Chemical Structure

Pinobanksin 3-acetate, CAS 52117-69-8

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1 mg	In stock	$ 83.00
5 mg	In stock	$ 263.00
10 mg	In stock	$ 393.00

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Description	Pinobanksin 3-acetate (3-O-Acetylpinobanksin), a flavonoid derivative, is a strong antioxidant found in sunflowers and honey that inhibits LDL peroxidation.
Targets&IC50	PANC1 cells:17.9 μM, PANC1 cells:9.1 μM
In vitro	Two new phenylallylflavanones, (2R,3R)-6-[1-(4'-hydroxy-3'-methoxyphenyl)prop-2-en-1-yl]pinobanksin (1) and (2R,3R)-6-[1-(4'-hydroxy-3'-methoxyphenyl)prop-2-en-1-yl]Pinobanksin 3-acetate (2) were isolated from a methanolic extract of Mexican propolis. Both compounds (1, 2) exhibited preferential cytotoxic activity against PANC-1 human pancreatic cancer cells in a nutrient-deprived medium with the concentration at which 50% of cells died preferentially in NDM (PC₅₀) values of 17.9 μM and 9.1 μM, respectively.[1]
Source	Natural Products > Pinaceae > Pinus

Synonyms	3-O-Acetylpinobanksin
Molecular Weight	314.29
Formula	C17H14O6
CAS No.	52117-69-8

Storage

store at low temperature,keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 90.0 mg/mL (286.4 mM), Sonification is recommended.

References and Literature

1. Li F, et al. Two new cytotoxic phenylallylflavanones from Mexican propolis. Chem Pharm Bull (Tokyo). 2011;59(9):1194-1196. 2. Xin BR, et al. A new flavonone from seeds of Alpinia katsumadai and its neuroprotective effect on PC12 cells. Zhongguo Zhong Yao Za Zhi. 2014;39(14):2674-2678. 3. Gobbo-Neto L, et al. Negative ion 'chip-based' nanospray tandem mass spectrometry for the analysis of flavonoids in glandular trichomes of Lychnophora ericoides Mart. (Asteraceae). Rapid Commun Mass Spectrom. 2008;22(23):3802-3808. l

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Keywords

Pinobanksin 3-acetate 52117-69-8 Others oxidation-reduction Antioxidant 3-O-Acetylpinobanksin Pinobanksin inhibitor inhibit

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