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Pinobanksin
🥰Excellent
Catalog No. TN2076Cas No. 548-82-3
Alias 3,5,7-Trihydroxyflavanon
Pinobanksin is a natural flavonoid that induces apoptosis in B-cell lymphoma cell lines and SH-SY5Y cells. It is a potent antioxidant that inhibits the peroxidation of low-density lipoprotein (LDL) and is able to occupy the catalytic center of xanthine oxidase (XO) and thus inhibit it. Pinobanksin also exhibits antimicrobial, anti-inflammatory, antiparasitic, anti-mutagenic, anti-proliferative, and anti-angiogenic effects.
Pinobanksin
🥰Excellent
Catalog No. TN2076Alias 3,5,7-TrihydroxyflavanonCas No. 548-82-3
Pinobanksin is a natural flavonoid that induces apoptosis in B-cell lymphoma cell lines and SH-SY5Y cells. It is a potent antioxidant that inhibits the peroxidation of low-density lipoprotein (LDL) and is able to occupy the catalytic center of xanthine oxidase (XO) and thus inhibit it. Pinobanksin also exhibits antimicrobial, anti-inflammatory, antiparasitic, anti-mutagenic, anti-proliferative, and anti-angiogenic effects.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $70 | In Stock | |
| 5 mg | $168 | In Stock | |
| 10 mg | $248 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Pinobanksin is a natural flavonoid that induces apoptosis in B-cell lymphoma cell lines and SH-SY5Y cells. It is a potent antioxidant that inhibits the peroxidation of low-density lipoprotein (LDL) and is able to occupy the catalytic center of xanthine oxidase (XO) and thus inhibit it. Pinobanksin also exhibits antimicrobial, anti-inflammatory, antiparasitic, anti-mutagenic, anti-proliferative, and anti-angiogenic effects. |
| In vitro | Methods: PC12 cells were treated with Pinobanksin (0.1-1 mg/mL, 24 hours), and cell viability and ROS content were measured by MTT assay. Results: The survival rate of PC12 cells exceeded 85%, and Pinobanksin showed no significant toxicity. It could also reduce the intracellular ROS level by 31.82% at a concentration of 1 mg/mL, demonstrating the intracellular antioxidant effect of Pinobanksin. [2] |
| Alias | 3,5,7-Trihydroxyflavanon |
| Molecular Weight | 272.25 |
| Formula | C15H12O5 |
| Cas No. | 548-82-3 |
| Smiles | O=C1C=2C(O[C@@H]([C@H]1O)C3=CC=CC=C3)=CC(O)=CC2O |
| Relative Density. | 1.497g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (293.85 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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