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Sakuranetin

Catalog No. TN1126 CAS 2957-21-3

Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant effects

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Sakuranetin, CAS 2957-21-3

Pack Size	Availability	Price/USD
1 mg	In stock	$ 40.00
5 mg	In stock	$ 89.00
10 mg	In stock	$ 122.00
25 mg	In stock	$ 228.00
50 mg	In stock	$ 343.00
100 mg	In stock	$ 497.00
1 mL * 10 mM (in DMSO)	In stock	$ 98.00

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Purity: 99.65%

Purity: 99%

Biological Description

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Storage & Solubility Information

Description	Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant effects
In vitro	Young rice leaves in a resistant line exhibited hypersensitive reaction (HR) within 3 days post inoculation (dpi) of a spore suspension, and an increase in Sakuranetin was detected at 3 dpi, increasing to 4-fold at 4 dpi. In the susceptible line, increased Sakuranetin was detected at 4 dpi, but not at 3 dpi, by which a large fungus mass has accumulated without HR. Induced expression of a PA biosynthesis gene OsNOMT for naringenin 7-O-methyltransferase was found before accumulation of Sakuranetin in both cultivars. The antifungal activity of Sakuranetin was considerably higher than that of the major rice diterpenoid PA momilactone A in vitro and in vivo under similar experimental conditions. The decrease and detoxification of Sakuranetin were detected in both solid and liquid mycelium cultures, and they took place slower than those of momilactone A. Estimated local concentration of Sakuranetin at HR lesions was thought to be effective for fungus restriction, while that at enlarged lesions in susceptible rice was insufficient[1]
Source	Natural Products > Poaceae > Oryza

Molecular Weight	286.28
Formula	C16H14O5
CAS No.	2957-21-3

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 125 mg/mL (436.64 mM)

References and Literature

1. Analysis on blast fungus-responsive characters of a flavonoid phytoalexin sakuranetin; accumulation in infected rice leaves, antifungal activity and detoxification by fungus.Molecules. 2014 Aug 4;19(8):11404-18.

Related compound libraries

This product is contained In the following compound libraries：

Tyrosine Kinase Inhibitor Library Membrane Protein-targeted Compound Library Kinase Inhibitor Library Chinese Pharmacopoeia Natural Product Library Anti-Colorectal Cancer Compound Library Anti-Fungal Compound Library Anti-Hypertension Compound Library Anti-Obesity Compound Library DNA Damage & Repair Compound Library Anti-Tumor Natural Product Library

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Keywords

Sakuranetin 2957-21-3 Angiogenesis DNA Damage/DNA Repair Metabolism Microbiology/Virology NF-Κb Tyrosine Kinase/Adaptors VEGFR NF-κB Antifungal PPAR Fungal inhibit Inhibitor inhibitor

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