Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TP-064 is a potent and selective PRMT4 inhibitor. TP-064 includes inhibition of PRMT4 with IC50 < 10nM for methylation of H3 (1-25) and greater than 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. TP-064 inhibits the methylation of MED12 with IC50 = 43 nM in cell.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 32.00 | |
2 mg | In stock | $ 45.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 122.00 | |
25 mg | In stock | $ 257.00 | |
50 mg | In stock | $ 513.00 | |
100 mg | In stock | $ 748.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 73.00 |
Description | TP-064 is a potent and selective PRMT4 inhibitor. TP-064 includes inhibition of PRMT4 with IC50 < 10nM for methylation of H3 (1-25) and greater than 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. TP-064 inhibits the methylation of MED12 with IC50 = 43 nM in cell. |
Targets&IC50 | MED12:43 nM(IC50), BAF155:340 nM(IC50) |
Synonyms | TP 064 |
Molecular Weight | 458.6 |
Formula | C28H34N4O2 |
CAS No. | 2080306-20-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125mg/mL (272.57mM), ultrasonic and warming and heat to 60℃
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TP-064 2080306-20-1 Chromatin/Epigenetic Histone Methyltransferase anticancer inhibit TP 064 Inhibitor BAF155 TP064 MED12 CARM1 dimethylation PRMT4 inhibitor