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Tiamulin fumarate (Thiamutilin fumarate) is a semisynthetic diterpenoid antibiotic with antibacterial activity and inhibition of protein synthesis, which can be used to study pneumocystis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | Inquiry | In Stock | |
100 mg | $34 | In Stock | |
500 mg | $75 | In Stock | |
1 g | $108 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | Tiamulin fumarate (Thiamutilin fumarate) is a semisynthetic diterpenoid antibiotic with antibacterial activity and inhibition of protein synthesis, which can be used to study pneumocystis. |
In vitro | Tiamulin exhibits high activity against mycoplasma strains (Gloss M. gallisepticum, M. synoviae, M. meleagridis, and M. iowae), spirochetes (Brachyspira hyodysenteriae, Brachyspira innocens, B. pilosicoli, B. intermedia), and Gram-positive bacteria (Staphylococcus, Streptococcus, Clostridium, and Campylobacter spp), but its activity against Gram-negative bacteria (Bordetella, Klebsiella, Haemophilus, Clostridium, Campylobacter, and Corynebacterium spp) is relatively low[1]. |
In vivo | Tiamulin is highly effective in treating swine dysentery in both breeding and laying hens, with significant efficacy against B. pilosicoli and B. intermedia at a dose of 25 mg/kg body weight per day for 5 consecutive days [1]. |
Alias | Thiamutilin fumarate |
Molecular Weight | 609.81 |
Formula | C32H51NO8S |
Cas No. | 55297-96-6 |
Smiles | OC(=O)\C=C\C(O)=O.[H][C@@]12C(=O)CC[C@]11CC[C@@H](C)[C@@]2(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]1C)OC(=O)CSCCN(CC)CC |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 80 mg/mL (131.18 mM), Sonication is recommended. DMSO: 80 mg/mL (131.18 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
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