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Tricin

Catalog No. TN1068Cas No. 520-32-1

Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7.

Tricin

Tricin

Purity: 98.81%
Catalog No. TN1068Cas No. 520-32-1
Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7.
Pack SizePriceAvailabilityQuantity
2 mg$98In Stock
5 mg$129In Stock
10 mg$189In Stock
25 mg$378In Stock
50 mg$619In Stock
100 mg$877In Stock
500 mg$1,750In Stock
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Purity:98.81%
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Product Introduction

Bioactivity
Description
Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7.
In vitro
Methanol extract of Zizania latifolia was partitioned with EtOAc, n-BuOH, and H2O. From the EtOAc layers, a new flavonolignan along with a known flavone and three known flavonolignans, Tricin (1), salcolin A (2), salcolin B (3), and salcolin C (4), were isolated through repeated silica gel and ODS column chromatography. The chemical structure of the new flavonolignan was determined to be Tricin-4'-O-[erythro-β-guaiacyl-(7'-O-methyl)-glyceryl] ether and was named salcolin D (5) based on physicochemical and spectroscopic data, including FT-NMR and ESI-MS. All compounds were isolated for the first time from this plant. Compounds 2-5, Tricin derivatives, all exhibited higher anti-inflammatory and anti-allergy activities than Tricin. In particular, salcolin D (5) was shown to have the strongest inhibitory activity against LPS-induced NO production in RAW 264.7 cells as well as β-hexosaminidase release in IgE-sensitized RBL-2H3 cells[1]
Chemical Properties
Molecular Weight330.29
FormulaC17H14O7
Cas No.520-32-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 125 mg/mL (378.46 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0276 mL15.1382 mL30.2764 mL151.3821 mL
5 mM0.6055 mL3.0276 mL6.0553 mL30.2764 mL
10 mM0.3028 mL1.5138 mL3.0276 mL15.1382 mL
20 mM0.1514 mL0.7569 mL1.5138 mL7.5691 mL
50 mM0.0606 mL0.3028 mL0.6055 mL3.0276 mL
100 mM0.0303 mL0.1514 mL0.3028 mL1.5138 mL

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