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A-802715

A-802715
A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation and blood levels of anti-inflammatory substances such as interleukin 10 receptor and tumor necrosis factor receptor.
Catalog No. T14075Cas No. 107767-58-8
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Purity:96.29%
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A-802715

Catalog No. T14075Cas No. 107767-58-8

A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation and blood levels of anti-inflammatory substances such as interleukin 10 receptor and tumor necrosis factor receptor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$1295 days
2 mg$1765 days
5 mg$2635 days
10 mg$4195 days
25 mg$8285 days
1 mL x 10 mM (in DMSO)$1865 days
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Product Introduction

Bioactivity
Description
A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation and blood levels of anti-inflammatory substances such as interleukin 10 receptor and tumor necrosis factor receptor.
In vitro
The toxicity of the methylxanthine derivative A802715 was evaluated using vital dye staining assays against two human melanoma lines, Be11 and MeWo, and two human squamous cell carcinoma lines, 4197 and 4451. A802715 demonstrated the highest toxicity, with a TD50 of 0.9-1.1 mM. BrdU incorporation assays in p53 wt cells indicated that A802715 significantly enhances irradiation-induced suppression of S-phase entry. Depending on the p53 status, A802715 either prolongs the G2/M block or remains ineffective [1].
Chemical Properties
Molecular Weight322.4
FormulaC16H26N4O3
Cas No.107767-58-8
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (186.10 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1017 mL15.5087 mL31.0174 mL155.0868 mL
5 mM0.6203 mL3.1017 mL6.2035 mL31.0174 mL
10 mM0.3102 mL1.5509 mL3.1017 mL15.5087 mL
20 mM0.1551 mL0.7754 mL1.5509 mL7.7543 mL
50 mM0.0620 mL0.3102 mL0.6203 mL3.1017 mL
100 mM0.0310 mL0.1551 mL0.3102 mL1.5509 mL

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