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A-802715
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Catalog No. T14075Cas No. 107767-58-8
A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation and blood levels of anti-inflammatory substances such as interleukin 10 receptor and tumor necrosis factor receptor.
A-802715
😃Good
Purity: 96.29%
Catalog No. T14075Cas No. 107767-58-8
A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation and blood levels of anti-inflammatory substances such as interleukin 10 receptor and tumor necrosis factor receptor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $129 | 5 days | |
| 2 mg | $176 | 5 days | |
| 5 mg | $263 | 5 days | |
| 10 mg | $419 | 5 days | |
| 25 mg | $828 | 5 days | |
| 1 mL x 10 mM (in DMSO) | $186 | 5 days |
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Purity:96.29%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation and blood levels of anti-inflammatory substances such as interleukin 10 receptor and tumor necrosis factor receptor. |
| In vitro | The toxicity of the methylxanthine derivative A802715 was evaluated using vital dye staining assays against two human melanoma lines, Be11 and MeWo, and two human squamous cell carcinoma lines, 4197 and 4451. A802715 demonstrated the highest toxicity, with a TD50 of 0.9-1.1 mM. BrdU incorporation assays in p53 wt cells indicated that A802715 significantly enhances irradiation-induced suppression of S-phase entry. Depending on the p53 status, A802715 either prolongs the G2/M block or remains ineffective [1]. |
| Molecular Weight | 322.4 |
| Formula | C16H26N4O3 |
| Cas No. | 107767-58-8 |
| Smiles | CCCn1cnc2n(C)c(=O)n(CCCCC(C)(C)O)c(=O)c12 |
| Relative Density. | 1.22 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (186.10 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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