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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks | |
100 mg | Inquiry | 10-14 weeks |
Description | Aniline-MPB-amino-C3-PBD is a cytotoxic agent with a non-alkylating group and acts as a sequence-selective DNA minor-groove binding agent. |
In vitro | Aniline-MPB-amino-C3-PBD (compound 16) exhibits cytotoxicity with IC50 values of 77, 72, 79, 184.3, 61.5, and 145.6 nM for SW48, LIM1215, SW620, U138-MG, A431, and REH cells, respectively. It effectively stabilizes DNA with sequence specificity and demonstrates potent antibacterial effects against the gram-negative strain E. coli K12 with a potency of 2 pg/mL. |
Molecular Weight | 758.86 |
Formula | C42H46N8O6 |
Cas No. | 2412923-79-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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