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ANR 94

Catalog No. T22031 CAS 634924-89-3

ANR94 is a potent and selective adenosine A 2A receptor (AA 2A R) antagonist with an K i of 46 nM for hAA 2A R. ANR94 has the potential for Parkinson's disease research [1] [2].

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ANR 94, CAS 634924-89-3

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

ANR94 is a potent and selective adenosine A 2A receptor (AA 2A R) antagonist with an K i of 46 nM for hAA 2A R. ANR94 has the potential for Parkinson's disease research [1] [2].

Molecular Weight	207.23
Formula	C9H13N5O
CAS No.	634924-89-3

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 45.0 mg/mL (217.2 mM), ultrasonic and warming and heat to 60°C

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Volpini R, et al. Adenosine A2A receptor antagonists: new 8-substituted 9-ethyladenines as tools for in vivo rat models of Parkinson's disease. ChemMedChem. 2009;4(6):1010-1019. 2. Micioni Di Bonaventura MV, et al. Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats. J Psychopharmacol. 2019;33(12):1550-1561.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

ANR 94 634924-89-3 GPCR/G Protein Neuroscience Adenosine Receptor Inhibitor inhibitor inhibit

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