Shopping Cart
- Remove All
Your shopping cart is currently empty
Bay 41-4109 (less active enantiomer)
Catalog No. T10480Cas No. 476617-51-3
Bay 41-4109, a potent HBV inhibitor with an IC50 of 53 nM, exhibits greater activity compared to its less active enantiomer.
Bay 41-4109 (less active enantiomer)
Catalog No. T10480Cas No. 476617-51-3
Bay 41-4109, a potent HBV inhibitor with an IC50 of 53 nM, exhibits greater activity compared to its less active enantiomer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $293 | Backorder | |
| 10 mg | $443 | Backorder | |
| 50 mg | $1,323 | Backorder | |
| 100 mg | $1,850 | Backorder | |
| 200 mg | Inquiry | Backorder | |
| 500 mg | Inquiry | Backorder | |
| 1 mL x 10 mM (in DMSO) | $256 | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Bay 41-4109 (less active enantiomer)"
Tenofovir
Cited
TDF, PMPA, GS 1278
T1649147127-20-6
Tenofovir (GS 1278) is an adenine analog REVERSE TRANSC-RIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.
- $37
Size
QTY
CitedCetylpyridinium Chloride
Pristacin, Hexadecylpyridinium Chloride, Cetamium
T6439123-03-5
Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
- $30
Size
QTY
Tenofovir Disoproxil Fumarate Cited
Tenofovir DF, GS-1278 Disoproxil Fumarate
T2409L202138-50-9
Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is prescribed to treat HIV and chronic hepatitis B virus (HBV) in adults.
- $46
Size
QTY
CitedOsalmid Cited
Oxaphenamide, 4'-Hydroxysalicylanilide
T0353526-18-1
Osalmid (Oxaphenamide) is a choleretic drug, inhibits ribonucleotide reductase activity by targeting ribonucleotide reductase small subunit M2 (RRM2).
- $30
Size
QTY
Cited4-Hydroxyacetophenone
Piceol, p-Acetylphenol, 4'-Hydroxyacetophenone, 4-Acetylphenol
T375099-93-4
4-Hydroxyacetophenone (4-Acetylphenol) is a potent xanthine oxidase inhibitor.
- $41
Size
QTY
Osthole Cited
Ostol, Osthol, NSC 31868
T2848484-12-8
Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.
- $31
Size
QTY
CitedDoxorubicin hydrochloride
Cited
NSC 123127, Hydroxydaunorubicin hydrochloride, Doxorubicin (Adriamycin) HCl, DOX hydrochloride, Adriamycin
T102025316-40-9
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.
- $34
Size
QTY
CitedTelbivudine
NV 02B, L-Thymidine, Epavudine
T15133424-98-4
Telbivudine (NV 02B) is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of telbivudine is as a Nucleoside Reverse Transcriptase Inhibitor. The chemical classification of telbivudine is Nucleoside Analog.
- $40
Size
QTY
Bifendate
Bifendatatum
T327373536-69-3
Bifendate (Bifendatatum) is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.
- $32
Size
QTY
Thiamine hydrochloride Cited
Vitamin B1 hydrochloride, Vitamin B1, Thiamine HCl, Thiamine chloride hydrochloride
T089467-03-8
Thiamine hydrochloride (Vitamin B1) is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiamine hydrochloride (Vitamin B1) is phosphorylated by thiamine diphosphokinase to form active thiamine pyrophosphate (TPP), also known as cocarboxylase. TPP is a coenzyme for many enzymatic activities involving fatty acid, amino acid and carbohydrate metabolism.
- $50
Size
QTY
CitedRO8191 Cited
RO4948191, CDM-3008
T22142691868-88-9
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
- $38
Size
QTY
Cited4,5-Dicaffeoylquinic acid
Isochlorogenic acid C, 3,4-Dicaffeoylquinic acid
T2S115857378-72-0
1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.
- $38
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Bay 41-4109, a potent HBV inhibitor with an IC50 of 53 nM, exhibits greater activity compared to its less active enantiomer. |
| Targets&IC50 | HBV:53 nM |
| In vivo | BAY 41-4109 exhibits dose-dependent reductions in viral DNA levels in both the liver and plasma, demonstrating effectiveness commensurate with 3TC. It also diminishes the hepatitis B virus core antigen (HBcAg) in the livers of HBV-transgenic mice. Pharmacokinetic analyses reveal swift absorption, a 30% bioavailability in mice, and dose-proportional plasma concentrations, reaching approximately 60% in rats and dogs [1]. Furthermore, BAY41-4109 disrupts in vivo virus production through a mechanism that interacts with the viral capsid [2]. |
| Molecular Weight | 395.76 |
| Formula | C18H13ClF3N3O2 |
| Cas No. | 476617-51-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 37 mg/mL (93.49 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Bay 41-4109 (less active enantiomer) | purchase Bay 41-4109 (less active enantiomer) | Bay 41-4109 (less active enantiomer) cost | order Bay 41-4109 (less active enantiomer) | Bay 41-4109 (less active enantiomer) chemical structure | Bay 41-4109 (less active enantiomer) in vivo | Bay 41-4109 (less active enantiomer) formula | Bay 41-4109 (less active enantiomer) molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.