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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $46 | 5 days |
Description | BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1]. |
Targets&IC50 | Fas:79 nM |
In vitro | BI 99179 is potent in mouse hypothalamic N-42 cells with an IC50 of 0.6 μM and shows no significant LDH release in cytotoxicity assays up to 30 μM[1]. |
In vivo | BI 99179 exhibits an excellent pharmacokinetic profile following oral administration at a dose of 4 mg/kg in male Han/Wistar rats, showcasing a half-life (t1/2) of 3.0 hours[1]. |
Alias | BI99179 |
Molecular Weight | 391.46 |
Formula | C23H25N3O3 |
Cas No. | 1291779-76-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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