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Cefacetrile

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Catalog No. T30785Cas No. 10206-21-0
Alias Cephacetrile, Celospor, Cefacetrilum, Cefacetrilo, Cefacetril

Cefacetrile (Cephacetrile) is a broad-spectrum cephalosporin antibiotic with antimicrobial activity, used to study Gram-negative infections, acting similarly to cefotifen.

Cefacetrile

Cefacetrile

😃Good
Purity: 98.38%
Catalog No. T30785Alias Cephacetrile, Celospor, Cefacetrilum, Cefacetrilo, CefacetrilCas No. 10206-21-0
Cefacetrile (Cephacetrile) is a broad-spectrum cephalosporin antibiotic with antimicrobial activity, used to study Gram-negative infections, acting similarly to cefotifen.
Pack SizePriceAvailabilityQuantity
1 mg$49In Stock
5 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$1537-10 days
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Purity:98.38%
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Product Introduction

Bioactivity
Description
Cefacetrile (Cephacetrile) is a broad-spectrum cephalosporin antibiotic with antimicrobial activity, used to study Gram-negative infections, acting similarly to cefotifen.
In vitro
Inhibiting Staphylococcus aureus and Streptococcus pyogenes, cefacetrile is effective at concentrations less than 1 μg/mL[4].
In vivo
Administered subcutaneously at doses of 50, 100, and 500 mg/kg, cefacetrile does not alter fertility, gestation, and post-natal development of term fetuses in rats, and fertility and gestation in rabbits[3].At an intravenous dose of 1 g/kg, cefacetrile produces no nephrotoxicity in rabbits and rats[2].
AliasCephacetrile, Celospor, Cefacetrilum, Cefacetrilo, Cefacetril
Chemical Properties
Molecular Weight339.32
FormulaC13H13N3O6S
Cas No.10206-21-0
SmilesC(O)(=O)C=1N2[C@@]([C@H](NC(CC#N)=O)C2=O)(SCC1COC(C)=O)[H]
Relative Density.1.59g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (235.77 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9471 mL14.7354 mL29.4707 mL147.3535 mL
5 mM0.5894 mL2.9471 mL5.8941 mL29.4707 mL
10 mM0.2947 mL1.4735 mL2.9471 mL14.7354 mL
20 mM0.1474 mL0.7368 mL1.4735 mL7.3677 mL
50 mM0.0589 mL0.2947 mL0.5894 mL2.9471 mL
100 mM0.0295 mL0.1474 mL0.2947 mL1.4735 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

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