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Cromakalim

🥰Excellent
Catalog No. T21478Cas No. 94470-67-4
Alias BRL-34915, BRL34915, BRL 34915, (±)-Cromakalim

Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener and a smooth muscle relaxant.Cromakalim has antiepileptic and anticonvulsant activity and may be useful in studies of asthma and disorders associated with vasodilation.

Cromakalim

Cromakalim

🥰Excellent
Purity: 99.39%
Catalog No. T21478Alias BRL-34915, BRL34915, BRL 34915, (±)-CromakalimCas No. 94470-67-4
Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener and a smooth muscle relaxant.Cromakalim has antiepileptic and anticonvulsant activity and may be useful in studies of asthma and disorders associated with vasodilation.
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Purity:99.39%
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Product Introduction

Bioactivity
Description
Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener and a smooth muscle relaxant.Cromakalim has antiepileptic and anticonvulsant activity and may be useful in studies of asthma and disorders associated with vasodilation.
AliasBRL-34915, BRL34915, BRL 34915, (±)-Cromakalim
Chemical Properties
Molecular Weight286.33
FormulaC16H18N2O3
Cas No.94470-67-4
SmilesCC1(C)Oc2ccc(cc2[C@@H]([C@H]1O)N1CCCC1=O)C#N
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: Insoluble
DMSO: 50 mg/mL (174.62 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4925 mL17.4624 mL34.9247 mL174.6237 mL
5 mM0.6985 mL3.4925 mL6.9849 mL34.9247 mL
10 mM0.3492 mL1.7462 mL3.4925 mL17.4624 mL
20 mM0.1746 mL0.8731 mL1.7462 mL8.7312 mL
50 mM0.0698 mL0.3492 mL0.6985 mL3.4925 mL
100 mM0.0349 mL0.1746 mL0.3492 mL1.7462 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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