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CYP17-IN-1
🥰Excellent
Catalog No. T10923Cas No. 2093317-51-0
CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.
CYP17-IN-1
🥰Excellent
Purity: 99.17%
Catalog No. T10923Cas No. 2093317-51-0
CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 111 € | In Stock | |
| 2 mg | 166 € | In Stock | |
| 5 mg | 254 € | In Stock | |
| 10 mg | 374 € | In Stock | |
| 25 mg | 562 € | In Stock | |
| 50 mg | 786 € | In Stock | |
| 100 mg | Inquiry | In Stock |
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Purity:99.17%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM. |
| Targets&IC50 | CYP17 (human):20.1 nM , CYP17 (rat):15.8 nM |
| In vitro | The IC50 value of CYP17-IN-1 for CYP3A4 is 8.5 µM[1]. |
| In vivo | CYP17-IN-1 dose-dependently reduced plasma testosterone levels in Sprague-Dawley rats[1]. |
| Molecular Weight | 312.4 |
| Formula | C18H17FN2S |
| Cas No. | 2093317-51-0 |
| Smiles | FC=1C=C2C3=C(SC2=CC1)CN(CC=4C(C)=CC=NC4)CC3 |
| Relative Density. | 1.285 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 3.12 mg/mL (10 mM), Sonication is recommended.  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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