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Detomidine carboxylic acid
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Catalog No. T11010Cas No. 115664-39-6
Detomidine carboxylic acid is the main urine metabolite of detomidine. Detomidine is a synthetic α2-adrenergic agonist and an animal analgesic. Detomidine also has heart and breathing effects, and has a diuretic effect.
Detomidine carboxylic acid
😃Good
Catalog No. T11010Cas No. 115664-39-6
Detomidine carboxylic acid is the main urine metabolite of detomidine. Detomidine is a synthetic α2-adrenergic agonist and an animal analgesic. Detomidine also has heart and breathing effects, and has a diuretic effect.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Detomidine carboxylic acid is the main urine metabolite of detomidine. Detomidine is a synthetic α2-adrenergic agonist and an animal analgesic. Detomidine also has heart and breathing effects, and has a diuretic effect. |
| In vivo | After oral administration of Detomidine, an analgesic sedative for large animals, to two stallions and intravenous injection of [3H]-Detomidine into mares, the metabolites in horse urine were studied. After oral doses, a combination of totomidine carboxylic acid and hydroxytomtomidine glucuronic acid was identified in the urine. About 12 hours after the intravenous injection, about half of the radioactivity of [3H]-tomtomidine was excreted into the urine. Dose (80μg/kg). Compared with the highest urine output 2 to 5 hours after urination, most excretion occurs between 5 and 12 hours. The main radioactive metabolite in urine is totomidine carboxylic acid. In all collected urine fractions, totomidine carboxylic acid accounts for more than two-thirds of the total metabolites. |
| Molecular Weight | 216.24 |
| Formula | C12H12N2O2 |
| Cas No. | 115664-39-6 |
| Relative Density. | 1.278g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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