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DIPQUO hydrochloride

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Purity:98.37%

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COA HNMR HPLC

DIPQUO hydrochloride

Catalog No. T11048L

DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.

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Pack Size	Price	Availability
1 mg	$107	In Stock
5 mg	$190	In Stock
10 mg	$316	In Stock
25 mg	$497	In Stock
50 mg	$693	In Stock
100 mg	$954	In Stock
500 mg	$1,900	In Stock
1 mL x 10 mM (in DMSO)	$211	In Stock

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Product Introduction

Bioactivity

Description	DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
In vitro	ALP activity was measured using a fluorescent emission assay as a reporter for enzymatic digestion of ALP substrate in lysates derived from C2C12 myoblasts, DIPQUO shows EC50 of 6.27 μM[1].
Alias	DIPQUO hydrochloride(1269365-82-3 Free base)

Chemical Properties

Molecular Weight	351.83
Formula	C20H18ClN3O
Cas No.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (142.11 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8423 mL	14.2114 mL	28.4228 mL	142.1141 mL
5 mM	0.5685 mL	2.8423 mL	5.6846 mL	28.4228 mL
10 mM	0.2842 mL	1.4211 mL	2.8423 mL	14.2114 mL
20 mM	0.1421 mL	0.7106 mL	1.4211 mL	7.1057 mL
50 mM	0.0568 mL	0.2842 mL	0.5685 mL	2.8423 mL
100 mM	0.0284 mL	0.1421 mL	0.2842 mL	1.4211 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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