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DIPQUO hydrochloride

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Catalog No. T11048L
Alias DIPQUO hydrochloride(1269365-82-3 Free base)

DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.

DIPQUO hydrochloride

DIPQUO hydrochloride

🥰Excellent
Purity: 98.37%
Catalog No. T11048LAlias DIPQUO hydrochloride(1269365-82-3 Free base)
DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
Pack SizePriceAvailabilityQuantity
1 mg$64In Stock
5 mg$113In Stock
10 mg$190In Stock
25 mg$298In Stock
50 mg$416In Stock
100 mg$572In Stock
200 mg$773In Stock
1 mL x 10 mM (in DMSO)$127In Stock
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Purity:98.37%
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Product Introduction

Bioactivity
Description
DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
In vitro
ALP activity was measured using a fluorescent emission assay as a reporter for enzymatic digestion of ALP substrate in lysates derived from C2C12 myoblasts, DIPQUO shows EC50 of 6.27 μM[1].
AliasDIPQUO hydrochloride(1269365-82-3 Free base)
Chemical Properties
Molecular Weight351.83
FormulaC20H18ClN3O
SmilesO=C1NC2=C(C=C1C3=C(C4=CC=CC=C4)N=CN3)C=C(C)C=C2C.Cl
Relative Density.no data available
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (142.11 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8423 mL14.2114 mL28.4228 mL142.1141 mL
5 mM0.5685 mL2.8423 mL5.6846 mL28.4228 mL
10 mM0.2842 mL1.4211 mL2.8423 mL14.2114 mL
20 mM0.1421 mL0.7106 mL1.4211 mL7.1057 mL
50 mM0.0568 mL0.2842 mL0.5685 mL2.8423 mL
100 mM0.0284 mL0.1421 mL0.2842 mL1.4211 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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