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Glycogen phosphorylase-IN-1
Catalog No. T37577Cas No. 648926-15-2
Glycogen phosphorylase-IN-1 is a selective and potent inhibitor of human hepatic glycogen phosphorylase (hlGPa) with inhibitory effects on hlGPa activity and on hepatocyte glycogen-derived glucose production, and can be used in the study of type 2 diabetes mellitus and canine lupus.
Glycogen phosphorylase-IN-1
Catalog No. T37577Cas No. 648926-15-2
Glycogen phosphorylase-IN-1 is a selective and potent inhibitor of human hepatic glycogen phosphorylase (hlGPa) with inhibitory effects on hlGPa activity and on hepatocyte glycogen-derived glucose production, and can be used in the study of type 2 diabetes mellitus and canine lupus.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $229 | In Stock | |
| 5 mg | $688 | In Stock | |
| 10 mg | $983 | In Stock | |
| 25 mg | $1,460 | In Stock | |
| 50 mg | $1,960 | In Stock | |
| 100 mg | $2,650 | In Stock |
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Purity:98.01%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Glycogen phosphorylase-IN-1 is a selective and potent inhibitor of human hepatic glycogen phosphorylase (hlGPa) with inhibitory effects on hlGPa activity and on hepatocyte glycogen-derived glucose production, and can be used in the study of type 2 diabetes mellitus and canine lupus. |
| In vivo | In the glucagon-stimulated hyperglycemia model in Wistar rats, Glycogen phosphorylase-IN-1 (5 mg/kg; administered via intravenous injection, single dose) was able to reduce blood glucose levels[1]. |
| Molecular Weight | 412.78 |
| Formula | C17H15ClF2N4O4 |
| Cas No. | 648926-15-2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | DMF: 2 mg/mL (4.85 mM), Sonication is recommended. DMSO: 2 mg/mL (4.85 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMF/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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