Shopping Cart
- Remove All
Your shopping cart is currently empty
Glycogen phosphorylase-IN-1
🥰Excellent
Catalog No. T37577Cas No. 648926-15-2
Glycogen phosphorylase-IN-1 is a selective and potent inhibitor of human hepatic glycogen phosphorylase (hlGPa) with inhibitory effects on hlGPa activity and on hepatocyte glycogen-derived glucose production, and can be used in the study of type 2 diabetes mellitus and canine lupus.
Glycogen phosphorylase-IN-1
🥰Excellent
Purity: 98.01%
Catalog No. T37577Cas No. 648926-15-2
Glycogen phosphorylase-IN-1 is a selective and potent inhibitor of human hepatic glycogen phosphorylase (hlGPa) with inhibitory effects on hlGPa activity and on hepatocyte glycogen-derived glucose production, and can be used in the study of type 2 diabetes mellitus and canine lupus.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $229 | In Stock | |
| 5 mg | $688 | In Stock | |
| 10 mg | $983 | In Stock | |
| 25 mg | $1,460 | In Stock | |
| 50 mg | $1,960 | In Stock | |
| 100 mg | $2,650 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Glycogen phosphorylase-IN-1"
L-Ascorbic acid 2-phosphate magnesium
2-Phospho-L-ascorbic acid magnesium
T19389113170-55-1
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) functions as an antioxidant and stimulates hepatocyte growth factor (HGF) production. This long-acting vitamin C derivative promotes collagen formation and expression.
- $41
Size
QTY
Disodium monofluorophosphate
NSC248
T074510163-15-2
Disodium monofluorophosphate (NSC248) is a competitive inhibitor of pyruvate kinase and alkaline phosphatase, which also irreversibly inhibits phosphorylase phosphatase.
- $29
Size
QTY
(-)-p-Bromotetramisole Oxalate
L-p-Bromotetramisole oxalate, 6-Bromolevamisole oxalate, (-)-p-Bromolevamisole oxalate
T635362284-79-1
(-)-p-Bromotetramisole Oxalate (6-Bromolevamisole oxalate) is a potent and non-specific inhibitor of alkaline phosphatase.
- $31
Size
QTY
Calcium glycerophosphate
T6025427214-00-2
Calcium glycerophosphate(CaGP) is an inhibitor of intestinal alkaline phosphatase F3. Calcium glycerophosphate can be a source of calcium and phosphorus in total parenteral nutrition solutions [1] [2].
- $29
Size
QTY
Uric Acid
Urate, Lithic acid, 2,6,8-Trioxypurine, 2,6,8-Trioxopurine, 2,6,8-Trihydroxypurine
T062669-93-2
Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
- $42
Size
QTY
AVE5688
T10421613260-13-2In house
AVE5688, an inhibitor of glycogen phosphorylase (GP), has IC50 values of 430 nM and 915 nM, and Kd values of 170 nM and 530 nM for rmGPb and rmGPa, respectively. It is suitable for research on type 2 diabetes.
- $282
Size
QTY
Tracheloside
T385533464-71-0
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml).
- $37
Size
QTY
CP-91149
T6455186392-40-5
CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
- $30
Size
QTY
DIPQUO hydrochloride
DIPQUO hydrochloride(1269365-82-3 Free base)
T11048LIn house
DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
- $64
Size
QTY
H-HomoArg-OH.HCl
NSC 145416, L-Homoarginine hydrochloride, L(+)-Homoarginine hydrochloride
T39381483-01-8
H-HomoArg-OH.HCl (L-Homoarginine hydrochloride) is a specific inhibitor of liver-type alkaline phosphatase.
- $29
Size
QTY
H-HoArg-OH
T8103156-86-5
H-HoArg-OH (a homologue of arginine) is a potent inhibitor of human liver and bone alkaline phosphatase.
- $29
Size
QTY
Ingliforib
GPi 296, CP 368296
T8493186392-65-4
Ingliforib (CP 368296) is a novel glycogen phosphorylase inhibitor with antihyperglycemic and cardioprotective properties.
- $50
Size
QTY
Select Batch
Purity:98.01%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Glycogen phosphorylase-IN-1 is a selective and potent inhibitor of human hepatic glycogen phosphorylase (hlGPa) with inhibitory effects on hlGPa activity and on hepatocyte glycogen-derived glucose production, and can be used in the study of type 2 diabetes mellitus and canine lupus. |
| In vivo | In the glucagon-stimulated hyperglycemia model in Wistar rats, Glycogen phosphorylase-IN-1 (5 mg/kg; administered via intravenous injection, single dose) was able to reduce blood glucose levels[1]. |
| Molecular Weight | 412.78 |
| Formula | C17H15ClF2N4O4 |
| Cas No. | 648926-15-2 |
| Smiles | O=C(NC(=O)C1=CC(F)=C(F)C=C1Cl)NC2=CC(=CC=C2OC)NC(=O)NC |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | DMF: 2 mg/mL (4.85 mM), Sonication is recommended. DMSO: 2 mg/mL (4.85 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMF/DMSO
| |||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Glycogen phosphorylase-IN-1 | purchase Glycogen phosphorylase-IN-1 | Glycogen phosphorylase-IN-1 cost | order Glycogen phosphorylase-IN-1 | Glycogen phosphorylase-IN-1 chemical structure | Glycogen phosphorylase-IN-1 in vivo | Glycogen phosphorylase-IN-1 formula | Glycogen phosphorylase-IN-1 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.