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Duostatin 5

Duostatin 5
Duostatin 5 (Duo-5) is a sea hare toxin analog commonly used in the synthesis of ADC compounds.
Catalog No. T77841Cas No. 2124210-34-8
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Purity:96.98%
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Duostatin 5

Catalog No. T77841Cas No. 2124210-34-8

Duostatin 5 (Duo-5) is a sea hare toxin analog commonly used in the synthesis of ADC compounds.
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Product Introduction

Bioactivity
Description
Duostatin 5 (Duo-5) is a sea hare toxin analog commonly used in the synthesis of ADC compounds.
Chemical Properties
Molecular Weight772.03
FormulaC40H69N9O6
Cas No.2124210-34-8
Storage & Solubility Information
Storagekeep away from direct sunlight,store under nitrogen | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (129.53 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2953 mL6.4764 mL12.9529 mL64.7643 mL
5 mM0.2591 mL1.2953 mL2.5906 mL12.9529 mL
10 mM0.1295 mL0.6476 mL1.2953 mL6.4764 mL
20 mM0.0648 mL0.3238 mL0.6476 mL3.2382 mL
50 mM0.0259 mL0.1295 mL0.2591 mL1.2953 mL
100 mM0.0130 mL0.0648 mL0.1295 mL0.6476 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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