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Enoticumab
🥰Excellent
Catalog No. T80615Cas No. 1192578-27-0
Alias SAR-153192, SAR153192, REGN-421, REGN421
Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody with anticancer activity that inhibits the growth of cancer cells.Enoticumab binds human Dll4 and disrupts Notch-mediated signaling.
Enoticumab
Enoticumab
🥰Excellent
Catalog No. T80615Alias SAR-153192, SAR153192, REGN-421, REGN421Cas No. 1192578-27-0
Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody with anticancer activity that inhibits the growth of cancer cells.Enoticumab binds human Dll4 and disrupts Notch-mediated signaling.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $263 | In Stock | |
| 5 mg | $795 | In Stock | |
| 10 mg | $1,260 | In Stock | |
| 25 mg | $1,870 | In Stock | |
| 50 mg | $2,520 | In Stock |
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CitedSelect Batch
Concentration:6.19 mg/mL
Contact us for more batch information
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Product Introduction
Bioactivity
Chemical Properties
| Description | Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody with anticancer activity that inhibits the growth of cancer cells.Enoticumab binds human Dll4 and disrupts Notch-mediated signaling. |
| In vivo | In an ovarian xenograft model, Enoticumab demonstrates specific in vivo activity. EGN421 (2.5 mg/kg, administered once weekly) achieved tumor growth inhibition of 86% and 83% in subcutaneous TOV-112D and intraperitoneal A2780 human tumor xenograft models in mice, respectively. [1] |
| Alias | SAR-153192, SAR153192, REGN-421, REGN421 |
| Cas No. | 1192578-27-0 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Related Tags: buy Enoticumab | purchase Enoticumab | Enoticumab cost | order Enoticumab | Enoticumab in vivo
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