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Product Introduction

Bioactivity

Description	Ethylmalonic acid is potentially toxic, non-carcinogenic, and has been associated with anorexia nervosa and methoxy decarboxylase deficiency.
Alias	alpha-Carboxybutyrate, 2-Ethylmalonic acid

Chemical Properties

Molecular Weight	132.11
Formula	C₅H₈O₄
Cas No.	601-75-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 10 mM

DMSO: 45 mg/mL (340.63 mM)

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	7.5694 mL	37.8472 mL	75.6945 mL	378.4725 mL
5 mM	1.5139 mL	7.5694 mL	15.1389 mL	75.6945 mL
10 mM	0.7569 mL	3.7847 mL	7.5694 mL	37.8472 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.3785 mL	1.8924 mL	3.7847 mL	18.9236 mL
50 mM	0.1514 mL	0.7569 mL	1.5139 mL	7.5694 mL
100 mM	0.0757 mL	0.3785 mL	0.7569 mL	3.7847 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Endogenous MetaboliteEthylmalonic acidα-CarboxybutyrateInhibitorinhibita-Carboxybutyrate