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Faltan

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Purity:95.49%

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COA HNMR HPLC

Faltan

Catalog No. T5872Cas No. 133-07-3

Faltan (Folpet),a widely used dicarboximide fungicide,induces tumors in the mouse gastrointestinal tract,primarily in the duodenum,and is also cytotoxic effect on human bronchial epithelial cells.

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1 g	$40	In Stock

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Product Introduction

Bioactivity

Description	Faltan (Folpet),a widely used dicarboximide fungicide,induces tumors in the mouse gastrointestinal tract,primarily in the duodenum,and is also cytotoxic effect on human bronchial epithelial cells.
In vitro	Folpan 80WG particles result in a rapid cytotoxic effect on human bronchial epithelial cells in vitro that could be in part explained by oxidative stress, characterised by membrane lipid peroxidation and ROS production[1].
Cell Research	Sub-confluent 16HBE14o- plated on collagen-coated 60 mm dishes were exposed to Folpan 80WG particles corresponding to 0, 1.85 and 3.70 g/cm^2 folpet (0, 10 and 20 μM) for 2, 4 and 24 h in RPMI-1640 medium w/o phenol red , w/o FCS, supplemented with 1% l-glutamine (200 mM), 1% penicillin (10^4 U/ml), 1% streptomycin (10 mg/ml) and 1% fungizone (25 μg/ml)[1].
Alias	Folpet

Chemical Properties

Molecular Weight	296.56
Formula	C9H4Cl3NO2S
Cas No.	133-07-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 125 mg/mL (421.50 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3720 mL	16.8600 mL	33.7200 mL	168.5999 mL
5 mM	0.6744 mL	3.3720 mL	6.7440 mL	33.7200 mL
10 mM	0.3372 mL	1.6860 mL	3.3720 mL	16.8600 mL
20 mM	0.1686 mL	0.8430 mL	1.6860 mL	8.4300 mL
50 mM	0.0674 mL	0.3372 mL	0.6744 mL	3.3720 mL
100 mM	0.0337 mL	0.1686 mL	0.3372 mL	1.6860 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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