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Fedovapagon

Catalog No. T15273Cas No. 347887-36-9
Alias VA483, A106483

Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. It can be used to study overactive bladder, nocturia, and painful bladder syndromes.

Fedovapagon

Fedovapagon

Purity: 99.33%
Catalog No. T15273Alias VA483, A106483Cas No. 347887-36-9
Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. It can be used to study overactive bladder, nocturia, and painful bladder syndromes.
Pack SizePriceAvailabilityQuantity
5 mg$113In Stock
10 mg$179In Stock
25 mg$392In Stock
50 mg$689In Stock
100 mg$973In Stock
1 mL x 10 mM (in DMSO)$126In Stock
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Purity:99.33%
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Product Introduction

Bioactivity
Description
Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. It can be used to study overactive bladder, nocturia, and painful bladder syndromes.
Targets&IC50
V2R:24 nM (EC50)
In vivo
In rats, oral administration of fedovapagon at a dose of 1 mg/kg results in an 81% inhibition rate of urine output[1].
AliasVA483, A106483
Chemical Properties
Molecular Weight462.58
FormulaC27H34N4O3
Cas No.347887-36-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (108.08 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1618 mL10.8089 mL21.6179 mL108.0894 mL
5 mM0.4324 mL2.1618 mL4.3236 mL21.6179 mL
10 mM0.2162 mL1.0809 mL2.1618 mL10.8089 mL
20 mM0.1081 mL0.5404 mL1.0809 mL5.4045 mL
50 mM0.0432 mL0.2162 mL0.4324 mL2.1618 mL
100 mM0.0216 mL0.1081 mL0.2162 mL1.0809 mL

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