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Fedovapagon
Catalog No. T15273Cas No. 347887-36-9
Alias VA483, A106483
Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. It can be used to study overactive bladder, nocturia, and painful bladder syndromes.
Fedovapagon
Catalog No. T15273Alias VA483, A106483Cas No. 347887-36-9
Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. It can be used to study overactive bladder, nocturia, and painful bladder syndromes.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $113 | In Stock | |
| 10 mg | $179 | In Stock | |
| 25 mg | $392 | In Stock | |
| 50 mg | $689 | In Stock | |
| 100 mg | $973 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $126 | In Stock |
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Purity:99.33%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. It can be used to study overactive bladder, nocturia, and painful bladder syndromes. |
| Targets&IC50 | V2R:24 nM (EC50) |
| In vivo | In rats, oral administration of fedovapagon at a dose of 1 mg/kg results in an 81% inhibition rate of urine output[1]. |
| Alias | VA483, A106483 |
| Molecular Weight | 462.58 |
| Formula | C27H34N4O3 |
| Cas No. | 347887-36-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (108.08 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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