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Feniralstat (KVD-824) is a selective and highly efficient kallikrein inhibitor. It can be used for researching immune system diseases and cardiovascular diseases.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $198 | In Stock | |
5 mg | $519 | In Stock | |
10 mg | $743 | In Stock | |
25 mg | $1,520 | In Stock | |
50 mg | $1,980 | In Stock | |
1 mL x 10 mM (in DMSO) | $590 | In Stock |
Description | Feniralstat (KVD-824) is a selective and highly efficient kallikrein inhibitor. It can be used for researching immune system diseases and cardiovascular diseases. |
Targets&IC50 | plasma kallikrein (pKal) (human):6.7 nM |
In vitro | Feniralstat (Compound 30) is a pyrazole derivative that potently inhibits kallikrein with an IC50 of 6.7 nM for human plasma kallikrein (pKal).Feniralstat weakly inhibits human KLK1, human FXIa, and human Factor XIIa (all with IC50s above 40 μM). [1] |
Alias | KVD-824, KVD824 |
Molecular Weight | 509.51 |
Formula | C26H25F2N5O4 |
Cas No. | 2166320-76-7 |
Smiles | O=C1C=CC(F)=CN1CC2=CC=C(C=C2)CN3N=C(C(=C3)C(=O)NCC4=NC=CC(OC)=C4F)COC |
Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80.00 mg/mL (157.01 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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