Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

FPI-1523 sodium

Catalog No. T38941Cas No. 1452459-52-7

FPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. It inhibited PBP2 with an IC50 of 3.2 μM and has a high level of antibacterial and considerable antimicrobial activity.

FPI-1523 sodium

FPI-1523 sodium

Purity: 99.42%
Catalog No. T38941Cas No. 1452459-52-7
FPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. It inhibited PBP2 with an IC50 of 3.2 μM and has a high level of antibacterial and considerable antimicrobial activity.
Pack SizePriceAvailabilityQuantity
1 mg$67In Stock
5 mg$163In Stock
10 mg$263In Stock
25 mg$538In Stock
50 mg$768In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "FPI-1523 sodium"

Select Batch
Purity:99.42%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
FPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. It inhibited PBP2 with an IC50 of 3.2 μM and has a high level of antibacterial and considerable antimicrobial activity.
In vitro
FPI-1523 sodium effectively inhibits both E. coli K12 and its PBP2, displaying minimum inhibitory concentrations (MIC) and half-maximal inhibitory concentrations (IC50) of 4 μg/mL and 0.4 μg/mL, respectively. Additionally, it demonstrates potent inhibition against E. coli BW25113 pGDP-2 transformants, irrespective of the presence of an empty vector or the expression of various β-lactamases, achieving low MIC values (1-2 μM).[1]
Chemical Properties
Molecular Weight344.27
FormulaC9H13N4NaO7S
Cas No.1452459-52-7
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (130.33 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9047 mL14.5235 mL29.0470 mL145.2348 mL
5 mM0.5809 mL2.9047 mL5.8094 mL29.0470 mL
10 mM0.2905 mL1.4523 mL2.9047 mL14.5235 mL
20 mM0.1452 mL0.7262 mL1.4523 mL7.2617 mL
50 mM0.0581 mL0.2905 mL0.5809 mL2.9047 mL
100 mM0.0290 mL0.1452 mL0.2905 mL1.4523 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy FPI-1523 sodium | purchase FPI-1523 sodium | FPI-1523 sodium cost | order FPI-1523 sodium | FPI-1523 sodium chemical structure | FPI-1523 sodium in vitro | FPI-1523 sodium formula | FPI-1523 sodium molecular weight