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Fumonisin B1

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Catalog No. T15356Cas No. 116355-83-0
Alias Fumonisin-B1

Fumonisin B1 (Fumonisin-B1) is a mycotoxin produced by Fusarium oxysporum that is widely present in crops, contaminating them and posing a significant food safety hazard.Fumonisin B1 is structurally a sphingosine and sphingomyelin analog, and inhibits the biosynthesis of complex sphingolipids through the inhibition of ceramidic synthases.

Fumonisin B1

Fumonisin B1

😃Good
Catalog No. T15356Alias Fumonisin-B1Cas No. 116355-83-0
Fumonisin B1 (Fumonisin-B1) is a mycotoxin produced by Fusarium oxysporum that is widely present in crops, contaminating them and posing a significant food safety hazard.Fumonisin B1 is structurally a sphingosine and sphingomyelin analog, and inhibits the biosynthesis of complex sphingolipids through the inhibition of ceramidic synthases.
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1 mg$29835 days
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Product Introduction

Bioactivity
Description
Fumonisin B1 (Fumonisin-B1) is a mycotoxin produced by Fusarium oxysporum that is widely present in crops, contaminating them and posing a significant food safety hazard.Fumonisin B1 is structurally a sphingosine and sphingomyelin analog, and inhibits the biosynthesis of complex sphingolipids through the inhibition of ceramidic synthases.
In vitro
The mRNA expression of P21 was significantly increased after 0.1 μmol/L Fumonisin B1 treatment, and the mRNA expression of P21 was significantly decreased after 10.0 and 100.0 μmol / l Fumonisin B1 treatment[1].
AliasFumonisin-B1
Chemical Properties
Molecular Weight721.83
FormulaC34H59NO15
Cas No.116355-83-0
SmilesO.CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)C(C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 16 mg/mL (22.17 mM), Sonication is recommended.
Methanol: 5 mg/mL (6.93 mM), Sonication is recommended.
Solution Preparation Table
Methanol/H2O
1mg5mg10mg50mg
1 mM1.3854 mL6.9268 mL13.8537 mL69.2684 mL
5 mM0.2771 mL1.3854 mL2.7707 mL13.8537 mL
H2O
1mg5mg10mg50mg
10 mM0.1385 mL0.6927 mL1.3854 mL6.9268 mL
20 mM0.0693 mL0.3463 mL0.6927 mL3.4634 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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