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Fumonisin B1

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Fumonisin B1

Catalog No. T15356Cas No. 116355-83-0

Fumonisin B1 (Fumonisin-B1) is a mycotoxin produced by Fusarium oxysporum that is widely present in crops, contaminating them and posing a significant food safety hazard.Fumonisin B1 is structurally a sphingosine and sphingomyelin analog, and inhibits the biosynthesis of complex sphingolipids through the inhibition of ceramidic synthases.

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Pack Size	Price	Availability	Quantity
1 mg	$222	35 days

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Product Introduction

Bioactivity

Description	Fumonisin B1 (Fumonisin-B1) is a mycotoxin produced by Fusarium oxysporum that is widely present in crops, contaminating them and posing a significant food safety hazard.Fumonisin B1 is structurally a sphingosine and sphingomyelin analog, and inhibits the biosynthesis of complex sphingolipids through the inhibition of ceramidic synthases.
In vitro	The mRNA expression of P21 was significantly increased after 0.1 μmol/L Fumonisin B1 treatment, and the mRNA expression of P21 was significantly decreased after 10.0 and 100.0 μmol / l Fumonisin B1 treatment[1].
Alias	Fumonisin-B1

Chemical Properties

Molecular Weight	721.83
Formula	C34H59NO15
Cas No.	116355-83-0

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 16 mg/mL (22.17 mM), Sonication is recommended.

Methanol: 5 mg/mL (6.93 mM), Sonication is recommended.

Solution Preparation Table

H2O/Methanol

	1mg	5mg	10mg	50mg
1 mM	1.3854 mL	6.9268 mL	13.8537 mL	69.2684 mL
5 mM	0.2771 mL	1.3854 mL	2.7707 mL	13.8537 mL

H2O

	1mg	5mg	10mg	50mg
10 mM	0.1385 mL	0.6927 mL	1.3854 mL	6.9268 mL
20 mM	0.0693 mL	0.3463 mL	0.6927 mL	3.4634 mL
50 mM	0.0277 mL	0.1385 mL	0.2771 mL	1.3854 mL
100 mM	0.0139 mL	0.0693 mL	0.1385 mL	0.6927 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc