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Gontivimab
🥰Excellent
Catalog No. T77027Cas No. 1257358-38-5
Alias VR-465, VR465, ALX-0171, ALX0171
Gontivimab (ALX-0171) is a trivalent nanobody targeting the hRSV fusion (F) protein with anti-RSV antiviral properties for the study of respiratory syncytial virus infections.
Gontivimab
Gontivimab
🥰Excellent
Catalog No. T77027Alias VR-465, VR465, ALX-0171, ALX0171Cas No. 1257358-38-5
Gontivimab (ALX-0171) is a trivalent nanobody targeting the hRSV fusion (F) protein with anti-RSV antiviral properties for the study of respiratory syncytial virus infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $483 | In Stock | |
| 10 mg | $692 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,490 | In Stock |
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Concentration:6.37 mg/mL
Purity:≥95% (SDS-PAGE/SEC-HPLC)
Contact us for more batch information
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Product Introduction
Bioactivity
Chemical Properties
| Description | Gontivimab (ALX-0171) is a trivalent nanobody targeting the hRSV fusion (F) protein with anti-RSV antiviral properties for the study of respiratory syncytial virus infections. |
| Targets&IC50 | RSV A strains:0.1 nM |
| In vitro | Gontivimab (0-100,000 nM) exhibited antiviral effects with IC50 values of 0.1 nM and 0.4 nM against RSV-A and RSV-B 18537 strains, respectively.[1] Gontivimab binds to antigenic site II of the F protein.[1] Gontivimab binds to antigenic site II of the F protein.[1] |
| In vivo | Gontivimab (1-68 mg/kg; administered intranasally or by nebulization) reduces RSV load in the nasal cavity and lungs of rats.[1] Gontivimab has been shown to reduce RSV load in the nasal cavity and lungs of rats. [1] |
| Alias | VR-465, VR465, ALX-0171, ALX0171 |
| Cas No. | 1257358-38-5 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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