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Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (HBV) activity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $320 | Backorder | |
1 mL x 10 mM (in DMSO) | $490 | Backorder |
Description | Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (HBV) activity. |
In vitro | Herpetin (HPT), Herpetone (HPO), and herpetfluorenone (HPF) were isolated from HS and identified using HR-ESI-MS and NMR. Different concentrations of the drugs were added to the HepG2.2.15 cells. Cell toxicity was observed with an MTT assay, cell culture supernatants were collected, and HBsAg and HBeAg were detected by ELISA. The content of HBV DNA was determined via quantitative polymerase chain reaction (PCR) with fluorescent probes. The 50% toxicity concentration (TC50) of HPF was 531.48 μg/mL, suggesting that this species is less toxic than HPT and HPO. |
Molecular Weight | 522.55 |
Formula | C29H30O9 |
Cas No. | 951677-22-8 |
Relative Density. | 1.31g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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