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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $59 | In Stock | |
5 mg | $136 | In Stock | |
10 mg | $198 | In Stock | |
25 mg | $328 | In Stock | |
50 mg | $491 | In Stock | |
100 mg | $716 | In Stock | |
500 mg | $1,480 | In Stock |
Description | Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane. |
In vitro | Iberin inhibits neuroblastoma cell growth in a dose- and time-dependent manner and inhibits the expression of cyclin-dependent kinase Cdk2, Cdk4, and Cdk6 proteins. Iberin increases the apoptotic cell death and activates caspase-9, caspase-3, and PARP[2]. |
In vivo | Iberin enhances tissue levels of the phase II detoxification enzymes quinone reductase and GST in a variety of rat tissues[5]. |
Alias | NSC 321801 |
Molecular Weight | 163.26 |
Formula | C5H9NOS2 |
Cas No. | 505-44-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 9.0 mg/mL (55.1 mM) DMSO: 279.0 mg/mL (1708.9 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
DMSO
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