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Iberin

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Catalog No. T15544Cas No. 505-44-2
Alias NSC 321801

Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane.

Iberin

Iberin

🥰Excellent
Purity: 99.67%
Catalog No. T15544Alias NSC 321801Cas No. 505-44-2
Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane.
Pack SizePriceAvailabilityQuantity
1 mg56 €In Stock
5 mg129 €In Stock
10 mg188 €In Stock
25 mg311 €In Stock
50 mg466 €In Stock
100 mg680 €In Stock
500 mg1.406 €In Stock
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Purity:99.67%
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Product Introduction

Bioactivity
Description
Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane.
Targets&IC50
Cell survival:2.3 μM
In vitro
Iberin inhibits neuroblastoma cell growth in a dose- and time-dependent manner and inhibits the expression of cyclin-dependent kinase Cdk2, Cdk4, and Cdk6 proteins. Iberin increases the apoptotic cell death and activates caspase-9, caspase-3, and PARP[2].
In vivo
Iberin enhances tissue levels of the phase II detoxification enzymes quinone reductase and GST in a variety of rat tissues[5].
AliasNSC 321801
Chemical Properties
Molecular Weight163.26
FormulaC5H9NOS2
Cas No.505-44-2
SmilesC(CS(C)=O)CN=C=S
Relative Density.1.142 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 9.0 mg/mL (55.1 mM), Sonication is recommended.
DMSO: 279.0 mg/mL (1708.9 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM6.1252 mL30.6260 mL61.2520 mL306.2600 mL
5 mM1.2250 mL6.1252 mL12.2504 mL61.2520 mL
10 mM0.6125 mL3.0626 mL6.1252 mL30.6260 mL
20 mM0.3063 mL1.5313 mL3.0626 mL15.3130 mL
50 mM0.1225 mL0.6125 mL1.2250 mL6.1252 mL
DMSO
1mg5mg10mg50mg
100 mM0.0613 mL0.3063 mL0.6125 mL3.0626 mL

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