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Indanidine
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Catalog No. T11651Cas No. 85392-79-6
Indanidine is a highly selective and potent α-adrenergic agonist with antihypertensive activity.Indanidine is an α-adrenergic antagonist that can be used in the study of neurological disorders.
Indanidine
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Purity: 100%
Catalog No. T11651Cas No. 85392-79-6
Indanidine is a highly selective and potent α-adrenergic agonist with antihypertensive activity.Indanidine is an α-adrenergic antagonist that can be used in the study of neurological disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $700 | 6-8 weeks | |
| 5 mg | $1,800 | 6-8 weeks |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Indanidine is a highly selective and potent α-adrenergic agonist with antihypertensive activity.Indanidine is an α-adrenergic antagonist that can be used in the study of neurological disorders. |
| In vivo | The selective alpha 1-adrenoceptor agonist, Indanidine, exhibited partial agonist behavior in the aorta without inducing significant contractions in the small mesenteric artery. Considering that Idazoxan and Indanidine have been reported to increase blood pressure in pithed rats via vascular alpha 1-adrenoceptors, these findings question the reliability of the small mesenteric artery assay as a predictor for in vivo alpha 1-adrenoceptor-mediated pressor activity[1]. |
| Molecular Weight | 215.25 |
| Formula | C11H13N5 |
| Cas No. | 85392-79-6 |
| Smiles | N1=C2C=CC=C(NC3=NCCN3)C2=CN1C |
| Relative Density. | 1.4g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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